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89 Results
Completed
Chronic Liver Disease in Urea Cycle Disorders
Urea cycle disorders (UCDs) are among the most common inborn errors of liver metabolism.With early diagnosis and improved treatments, the survival of individuals with UCDs has improved, and this improved …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Meclizine for Hepatocellular Carcinoma
The constitutive androstane receptor (CAR, NR1I3) is a nuclear receptor that plays a central role in hepatic detoxification of potentially toxic compounds, or xenobiotics. Chronic CAR activation by specific agonists …
Recruiting
Early Predictors of Necrotizing Enterocolitis in Neonates
The study will enroll premature, low birth weight infants in the Neonatal Intensive Care Units (NICU). Potential study subjects will be identified upon delivery, or transfer to the NICU, and …
Baylor Role: Lead Sponsor
Recruiting
Pediatric Acute Gastrointestinal Bleeding Registry
A. Specific Aims/Objectives: The goal of this study is to identify significant clinical and laboratory risk factors in pediatric patients with significant upper gastrointestinal bleeding. This is defined as bleeding …
Baylor Role: Collaborator
Completed
Metabolomics for Biomarker Discovery in Children With EoE
Eosinophilic esophagitis (EoE) is a disorder of the esophagus triggered by food and/or environmental allergens and is characterized by symptoms of esophageal dysfunction and eosinophilia of the esophagus. The standard …
Baylor Role: Collaborator
Completed
Gravity Assisted Technique for Esophageal Endoscopic Submucosal Dissection (ESD)
Early precancerous esophageal lesions and esophageal cancer, are a threatening illnesses with high mortality rate, so the early intervention is critical during the course of treatment, statistically, every year an …
Baylor Role: Lead Sponsor
Completed
Efficacy of Audio Recorded Guided Imagery vs Deep Breathing Exercises on Functional Gastrointestinal Pain Disorders
Children managed in primary care with a functional gastrointestinal pain disorder will be recruited and studied for this trial. After participants are deemed eligible, they will complete multiple questionnaires and …
Baylor Role: Lead Sponsor
Withdrawn
Trial- Dysphagia From ETT or GI Endoscopy
Patients between the ages of 5-17 with normal cognitive function presenting for Upper GI endoscopy will be considered for participation in this study. After consent is obtained from the parent/legal …
Baylor Role: Lead Sponsor
Completed
Detection of Exocrine Pancreatic Insufficiency in Patients With Diarrhea and Bloating
Exocrine pancreatic insufficiency (EPI) diagnosis can be challenging due to several reasons. First, the main symptoms of EPI such as diarrhea, loose stool, bloating or weight loss have low specificity …
Baylor Role: Lead Sponsor
Withdrawn
Factors Associated With Increased Risk of Bacteremia and Cholangitis in ERCP With Cholangioscopy
ERCP with cholangioscopy is becoming a widespread technique to treat complicated choledocholithiasis, document CBD clearance after stone extraction and to assess biliary duct strictures. During the procedure, a large amount …
Baylor Role: Lead Sponsor