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Fast-Fail Trials in Mood and Anxiety Spectrum Disorders; Kappa Opioid Receptor Phase 2a (External Link)
FAST-MAS addresses an important problem and critical barrier to progress in Mood and Anxiety Spectrum Disorders and if the aims of the project are achieved, FAST-MAS could shift scientific knowledge, …
Baylor Role:
Collaborator
Completed
Home Away From Home - Medical Outcomes (External Link)
This is a bidirectional observational cohort study. Participants will be patients less that 19 years of age at diagnosis receiving or having received chemotherapy for AML from seventeen participating pediatric …
Baylor Role:
Collaborator
Completed
Rapid Infusion Rituximab, Hematologic, Oncologic, and Rheumatologic Disorders (External Link)
The standard of care in patients receiving rituximab is to give the dose slowly and gradually increase the rate of rituximab until the full dose is given, which may take …
Baylor Role:
Lead Sponsor
Completed
Genomic Sequencing for Childhood Risk and Newborn Illness (External Link)
The objective of this research protocol is to conduct a randomized clinical trial to assess the benefits and risks of adding the information from a genomic sequencing report to physician-mediated …
Baylor Role:
Collaborator
Completed
Energetics and Function in Older Humans (External Link)
Data not available at present
Baylor Role:
Lead Sponsor
Completed
Comparative Efficacy of Phenylbutyrate (PBA) vs. Benzoate in Urea Cycle Disorders (External Link)
The investigators will study and compare how effectively sodium phenylbutyrate, sodium benzoate, and a combination of the two, help excrete nitrogen in healthy volunteers. Subject participation will require three, separate, …
Baylor Role:
Lead Sponsor
Completed
Fecal Microbiota Transplantation (FMT) for Treatment of Ulcerative Colitis in Children (External Link)
FMT RECIPIENTS: Participants will be recruited from the patient population treated by the Pediatric Gastroenterology, Hepatology, and Nutrition Section at Baylor College of Medicine/Texas Children's Hospital. I. Activities prior to …
Baylor Role:
Lead Sponsor
Completed
Use of Baxter Animated Retching Faces (BARF) Scale to Measure Nausea in Children Who Speak Spanish (External Link)
By default the most common objective outcome measure used in pediatric studies has been the incidence and number of emetic episodes. This measure, however, correlates poorly with the somatic subjective …
Baylor Role:
Lead Sponsor
Completed
Non-invasive Biomarkers of Fibrosis in Pediatric Liver Diseases (External Link)
Abnormal liver biochemical and function tests are frequently detected in symptomatic patients since many screening blood test panels routinely include them. A population-based survey in the United States conducted between …
Baylor Role:
Lead Sponsor
Completed
Clinical Use of Baxter Animated Retching Faces (BARF) Scale in Children (External Link)
Pediatric research in the management of nausea has been limited by the absence of a reliable method to quantify the intensity of this subjective symptom. In adults, the visual analog …
Baylor Role:
Lead Sponsor