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436 Results

Completed
A Randomized, Placebo-controlled, Tourette Syndrome Study. (External Link)
This study consists of three phases: Screening/Washout Phase, Double-Blind Phase and Taper Phase. SCREENING/WASHOUT PHASE: Your study doctor or his staff will review with you any medications that you are …
Baylor Role: Lead Sponsor
Completed
Physician Uncertainty Reduction for Hypertension (External Link)
BACKGROUND: A large amount of literature suggests that the majority of "uncontrolled" hypertensives are under medical care, and that lack of control is largely explained by physicians not intensifying treatment …
Baylor Role: Lead Sponsor
Completed
Taxotere and Adriamycin/Cytoxan (AC) Validation in Breast Cancer Patients (External Link)
Large clinical trials have confirmed the value of systemic adjuvant therapy in decreasing the risk of recurrence and death in patients with early breast cancer. However, the need to identify …
Baylor Role: Collaborator
Completed
Trial of Xyrem for Excessive Daytime Sleepiness and Sleep Disturbance in Parkinson's Disease (PD) (External Link)
Inclusion required an Epworth Sleepiness Scale (ESS) score greater than 10 and any subjective nocturnal sleep concern, usually insomnia. An acclimation and screening polysomnogram was performed to exclude subjects with …
Baylor Role: Lead Sponsor
Completed
Long-term Effects of Highly Active Anti-Retroviral Therapy on HIV-Infected Children (External Link)
BACKGROUND: HIV-infected children are often given HAART to reduce HIV-associated disease. The long-term effects and toxicities associated with this chronic therapy in children are unknown, but severe cardiotoxicity has been …
Baylor Role: Collaborator
Completed
Ability to Cope With Type 1 Diabetes (External Link)
Coping with type 1 diabetes can be very difficult. Type 1 diabetes is a very unique chronic disease because it requires constant attention to several responsibilities such as daily glucose …
Baylor Role: Lead Sponsor
Completed
Novel Treatment for Diastolic Heart Failure in Women (External Link)
Subjects with diastolic heart failure defined based on clinical symptoms, echocardiography diastology parameters and brain natriuretic peptide level will be randomized in a 1:1 fashion to either placebo or spironolactone …
Baylor Role: Lead Sponsor
Completed
Sleep, HIV Disease Progression, and Function in HIV Infected Children and Adolescents (External Link)
BACKGROUND: In the growing number of HIV infected youth and young adults, it is important to study the effects of HAART treatment on sleep patterns and related neurocognitive and psychosocial …
Baylor Role: Lead Sponsor
Completed
Ability to Cope With Type 1 Diabetes (External Link)
Coping with type 1 diabetes can be very difficult. Type 1 diabetes is a very unique chronic disease because it requires constant attention to several responsibilities such as daily glucose …
Baylor Role: Lead Sponsor
Completed
Cytotoxic T-Lymphocytes for the Prophylaxis of Cytomegalovirus After Allogeneic Stem Cell Transplant (External Link)
If the patient and their donor are eligible, we will take 100-120 ml (20-24 teaspoonfuls) of blood from the donor 3-4 weeks before the transplant. We will only take as …
Baylor Role: Lead Sponsor