Featured

Status

Health Topics

Any Category
Clear Filters

Search Clinical Trials

400 Results
Completed
Response of Clostridium Difficile Infection to Metronidazole Therapy
Clostridium difficile is a major cause of nosocomial infection. When this organism proliferates in the colon, usually as a result of prior antibiotic therapy in a hospitalized or otherwise debilitated …
Baylor Role: Collaborator
Completed
Effect of Curcumin on Lung Inflammation
Chronic obstructive pulmonary disease (COPD) and lung cancer are leading causes of death and health care use. Diffuse airways inflammation is seen in COPD and is thought to be the …
Baylor Role: Lead Sponsor
Completed
Study of Na-ASP-2 Human Hookworm Vaccine in Healthy Adults Without Evidence of Hookworm Infection
There is an urgent need for new tools to control human hookworm infection and to reduce its burden of disease in developing countries. This is especially true for children and …
Baylor Role: Lead Sponsor
Completed
Zoledronic Acid (ZOMETA) With Cyclophosphamide With Neuroblastoma and Cortical Bone Involvement
Zoledronic Acid (Zometa), a new generation, highly potent bisphosphonate used to treat osteoporosis and hypercalcemia of malignancy, is widely used in adult malignancies with potential for bone metastasis such as …
Baylor Role: Lead Sponsor
Withdrawn
Temozolomide and Topotecan in Treating Patients With Primary CNS Lymphoma
OBJECTIVES: Primary - Determine the complete radiologic response rate in patients with primary CNS lymphoma treated with salvage chemotherapy comprising temozolomide and topotecan. Secondary - Determine the median and failure-free …
Baylor Role: Collaborator
Completed
Association Between Response to Treatment of C. Diff Colitis and Anti-C.Diff Toxin Antibody
Clostridium difficile is the leading cause of nosocomial diarrheal disease associated with antibiotic therapy. This is a debilitating condition with substantial morbidity and mortality that may be around 2-3%. Current …
Baylor Role: Collaborator
Completed
Pharmacogenetics of Disulfiram for Cocaine
Dopamine, a type of neurotransmitter, is the brain's "feel good" chemical. The amount of dopamine in the body may be an important factor in how cocaine addicts respond to treatment. …
Baylor Role: Lead Sponsor
Completed
Lantus in the Treatment of Type 1 Diabetes Children
The landmark report of the diabetes control and complications trial (DCCT) trial has shown that intensive management delays and/or prevents complications in small vessels associated with Type 1 diabetes (T1DM). …
Baylor Role: Lead Sponsor
Terminated
Trial of Calcineurin Inhibitor-Sparing Immunosuppression Regimen in Pediatric Liver Transplantation
The objective of this study is to compare the effects of two liver transplant immunosuppression regimens on renal function. Patients receiving the standard combination of prednisone and high-dose tacrolimus, a …
Baylor Role: Lead Sponsor
Completed
Taxotere and Adriamycin/Cytoxan (AC) Validation in Breast Cancer Patients
Large clinical trials have confirmed the value of systemic adjuvant therapy in decreasing the risk of recurrence and death in patients with early breast cancer. However, the need to identify …
Baylor Role: Collaborator