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64 Results

Completed
Eradication of Helicobacter Pylori With a Lactobacillus Reuteri Strain Plus Proton Pump Inhibitor (External Link)
Aim of study This double-blind study will assess if the combination of PPI and a strain combination (Gastrus) of L.reuteri can yield higher eradication rates if doses are increased and …
Baylor Role: Collaborator
Withdrawn
Factors Associated With Increased Risk of Bacteremia and Cholangitis in ERCP With Cholangioscopy (External Link)
ERCP with cholangioscopy is becoming a widespread technique to treat complicated choledocholithiasis, document CBD clearance after stone extraction and to assess biliary duct strictures. During the procedure, a large amount …
Baylor Role: Lead Sponsor
Completed
Ceftaroline for Treatment of Hematogenously Acquired Staphylococcus Aureus Osteomyelitis in Children (External Link)
This is a Phase 1/2, open-label, single-center study to determine safety and tolerability of Ceftaroline in pediatric subjects 1 to 17 years of age (inclusive) with signs and symptoms of …
Baylor Role: Lead Sponsor
Completed
Home Away From Home - Medical Outcomes (External Link)
This is a bidirectional observational cohort study. Participants will be patients less that 19 years of age at diagnosis receiving or having received chemotherapy for AML from seventeen participating pediatric …
Baylor Role: Collaborator
Recruiting
Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae (External Link)
Open-label, dose-escalation clinical study in healthy, hookworm-naïve adults: - Study site: George Washington Medical Faculty Associates, Washington, DC - Number of participants: up to 30 in 3 cohorts of 10 …
Baylor Role: Lead Sponsor
Terminated
Efficacy of Micro-Patterned Foley Catheter to Reduce Catheter-Associated Urinary Tract Infection (External Link)
Roughly half of the two million nosocomial infections that occur each year are associated with the use of a medical device. Approximately 30 million urinary catheters are inserted each year …
Baylor Role: Lead Sponsor
Completed
Respiratory Viral Infections in Pediatric Transplantation (External Link)
The purpose of the study is to 1) Determine the incidence of respiratory viral infections diagnosed during the first year post SOT and HSCT; 2a) Determine the all-cause mortality within …
Baylor Role: Collaborator
Completed
Multivirus-specific T Cells for the Treatment of Virus Infections After Stem Cell Transplant (External Link)
These VST lines have been made at Baylor College of Medicine from donors for other transplant patients or other normal donors some of whom were from the National Marrow Donor …
Baylor Role: Collaborator
Terminated
Use Of Oral Fidaxomicin Vs. Oral Vancomycin For Clostridium Difficile Infection In Patients With Spinal Cord Injury (External Link)
In recent clinical trials, comparing oral Vancomycin versus oral Fidaxomicin to treat Clostridium difficile, oral Fidaxomicin was shown to be the same in effectiveness as oral Vancomycin, but showed a …
Baylor Role: Lead Sponsor
Completed
Catheter Biofilm Microbiome in Infected Neonatal Catheters. (External Link)
Catheter-associated bloodstream infections (CLABSIs) are a significant component of healthcare-associated infections (HAI),which are associated with significant mortality, morbidity and healthcare costs. Neonates are at higher risk for CLABSIs than children …
Baylor Role: Lead Sponsor