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Completed
A Pilot Project Exploring the Impact of Whole Genome Sequencing in Healthcare (External Link)
Whole genome sequencing (WGS) and whole exome sequencing (WES) services are currently available to and are being utilized by physicians and their patients in both research and clinical settings. The …
Baylor Role:
Collaborator
Terminated
Evaluating the Use of Exenatide in People With Type 2 Diabetes and Diastolic Heart Failure (External Link)
Diastolic heart failure is a life-threatening condition that occurs when the ventricles of the heart become stiff and do not fully relax, preventing the heart from properly filling with blood. …
Baylor Role:
Lead Sponsor
Unknown Status
The Cardiovascular Genetic and Therapeutic Implications of Muscular Dystrophy (External Link)
Objective(s) and Hypothesis(es): The objectives to be evaluated are as follows: Specific Hypothesis #1: Heart disease, specifically dilated cardiomyopathy, can be identified early in patients with muscular dystrophy and allow …
Baylor Role:
Lead Sponsor
Completed
Time to Defibrillation Using Automated External Defibrillators by Pediatric Residents in Simulated Cardiac Arrests (External Link)
Automated external defibrillators have improved survival for adult in hospital cardiac arrest. Automated external defibrillators are approved for children aged 1 year and older for out of hospital cardiac arrests. …
Baylor Role:
Lead Sponsor
Completed
Erythropoetin Neuroprotection for Neonatal Cardiac Surgery (External Link)
Hypothesis: Erythropoetin (EPO) will protect the neonatal brain in the perioperative period for congenital heart surgery. Using a prospective, randomized, placebo-controlled, double-blinded design, the specific aims of this study are: …
Baylor Role:
Lead Sponsor
Completed
Collaborative Care for Heart Failure Patients With the Metabolic Syndrome (External Link)
A striking feature of the Harris County Hospital District heart failure population is that the prevalence of obesity (50.8%) and the metabolic syndrome (48.9%) exceeds that of the general U.S. …
Baylor Role:
Lead Sponsor
Completed
The Effect of Diet and Exercise in Heart Failure (External Link)
A growing number of people in this country are overweight or obese. This is concerning as increasing weight has been shown to increase the risk of developing heart failure. However, …
Baylor Role:
Lead Sponsor
Completed
A Culturally Sensitive Values-Guided Aid for End of Life Decision-Making (External Link)
Background: End-of-life decision-making is an important aspect of providing quality healthcare, especially for the elderly population. Increasingly, the appropriateness of many of these decisions is being questioned. Some invasive procedures …
Baylor Role:
Collaborator
Completed
Physician Uncertainty Reduction for Hypertension (External Link)
BACKGROUND: A large amount of literature suggests that the majority of "uncontrolled" hypertensives are under medical care, and that lack of control is largely explained by physicians not intensifying treatment …
Baylor Role:
Lead Sponsor
Completed
Novel Treatment for Diastolic Heart Failure in Women (External Link)
Subjects with diastolic heart failure defined based on clinical symptoms, echocardiography diastology parameters and brain natriuretic peptide level will be randomized in a 1:1 fashion to either placebo or spironolactone …
Baylor Role:
Lead Sponsor