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Withdrawn
Study of Metformin With Simvastatin for Men With Prostate Carcinoma
Men who participate in this study will take both metformin and simvastatin every day. Both drugs are pills and can be taken at home. Subjects will be asked to take …
Completed
Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Performed Under General Anesthesia Versus Moderate Sedation
The purpose of the study is to determine if there are any differences in yield or safety of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) (a type of bronchoscopy with biopsy) …
Baylor Role: Lead Sponsor
Completed
Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With or Without Additional Adjuvant in Brazilian Adults
Human hookworm infection is a soil-transmitted helminth infection caused by the nematode parasites Necator americanus and Ancylostoma duodenale. It is one of the most common chronic infections of humans, afflicting …
Baylor Role: Lead Sponsor
Active, Not Recruiting
CYP19A1 Gene and Pharmacogenetics of Response to Testosterone Therapy
Estrogen has been gaining recognition as the primary hormone that regulates the male skeleton. Estrogen in males is mainly derived from the conversion of testosterone to estradiol by the enzyme …
Baylor Role: Collaborator
Completed
Pramipexole as a Treatment for Cocaine Dependence
In this protocol we propose to assess the impact of treatment with higher doses of the potent D2/3 agonist pramipexole, using the extended release preparation that has been shown to …
Baylor Role: Lead Sponsor
Completed
Exercise as a Behavioral Treatment for Cocaine Dependence
This proposal represents an important research effort with considerable public health significance in that it will provide detailed behavioral and physiological data for a non-pharmacological intervention to treat stimulant addiction. …
Baylor Role: Lead Sponsor
Terminated
Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia
Satisfactory pain control can generally be achieved after major surgery of the tibia through a combination of enteral and parenteral medications, neuraxial techniques (such as epidural analgesia), and/or regional techniques …
Baylor Role: Lead Sponsor
Completed
Pancreas Resection With and Without Drains
The rate of pancreatic fistula after pancreas resection is about 10% and surgeons have traditionally placed drains near the pancreatic anastomosis to control this potentially very serious complication. In recent …
Baylor Role: Lead Sponsor
Completed
A Trial Of Oral Chloral Hydrate Versus Intranasal Dexmedetomidine For Sedated Abr Exams
The purpose of this study is to compare the efficacy of oral chloral hydrate to intranasal dexmedetomidine for the successful completion of a sedated ABR exam (hearing exam).
Baylor Role: Lead Sponsor
Completed
Tranexamic Acid (TA) vs Combined Oral Contraceptive (COCP) Pilot Study
Subjects were randomized to one of two groups (group A or B). Group A received oral tranexamic acid at 1300 mg (two 650mg tablets), three times each day on days …
Baylor Role: Lead Sponsor