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Search Clinical Trials
Completed
The Role of Amylin and Glucagon in T1DM (External Link)
Objective: To develop a new treatment approach in the prevention of hypo and hyperglycemia in children with type 1diabetes. Background/Rationale: The diabetes control and complications trial (DCCT) showed that improving …
Baylor Role:
Lead Sponsor
Completed
Rituxan + BEAM and Auto Stem Cell Transplant for High Risk Lymphoma or Hodgkin's Disease (External Link)
Subjects will receive the chemotherapy through a plastic tube (catheter) placed into a vein under the collarbone. The antibody rituximab is given on the day of admission. The subject will …
Baylor Role:
Lead Sponsor
Completed
Anthrax Vaccine Clinical Trial to Assess Dose Reduction and Route Change (External Link)
This study is a 43-month prospective, randomized, double-blind, placebo-controlled comparison of immunogenicity and reactogenicity elicited by BioThrax given by different routes of administration (SQ versus IM) and dosing regimens (as …
Baylor Role:
Collaborator
Completed
Biologic Correlative Taxotere/AC (External Link)
Breast cancer and systemic chemotherapy: Systemic chemotherapy for operable breast cancer significantly decreases the risk of relapse and death. However, it is not possible to identify those patients at the …
Baylor Role:
Collaborator
Completed
Comparison of Sirolimus and Azathioprine in Lung Transplantation (External Link)
This multicenter prospective, randomized controlled clinical trial compared the open label use of sirolimus with that of azathioprine in a tacrolimus-based immunosuppression regimen. Eligible patients were identified during a 90-day …
Baylor Role:
Collaborator
Completed
PS-341 Followed by Removal of Prostate for Those With Prostate Cancer (External Link)
In murine and human xenograft tumor models, administration of PS-341 weekly was associated with significant antitumor activity. In primate studies using a schedule of twice weekly for six weeks, the …
Baylor Role:
Lead Sponsor
Completed
Treatment of Resistant Langerhans Cell Histiocytosis With ENBREL (External Link)
After subjects have completed the pretreatment evaluations, they will receive an injection of Enbrel - the study drug -(given under the skin) twice weekly. If the subjects disease stabilizes or …
Baylor Role:
Lead Sponsor
Completed
A Pharmacokinetic Study of Valacyclovir in Pediatric Oncology Patients (External Link)
In this study, patients will receive a single dose of oral valacyclovir. Blood samples will be drawn to evaluate the pharmacology (how the body handles the drug). Blood samples (less …
Baylor Role:
Lead Sponsor
Completed
Encouraging Calcium Absorption and Bone Formation During Early Puberty (External Link)
Rapid increases in bone mass occur during calcium absorption and bone calcium deposition during puberty, and these increases can enhance peak bone mass and ultimately decrease the lifetime risk of …
Baylor Role:
Lead Sponsor
Completed
Evaluating the Use of RFT5-dgA to Deplete Alloreactive Cells Prior to Haploidentical Stem Cell Transplantation (External Link)
Patients will receive cytosine arabinoside (3g/m^2) IV every 12 hours for 6 doses starting at 1400 hours on day -8. Cyclophosphamide (45mg/kg) will be given on Day -7 and Day …
Baylor Role:
Lead Sponsor