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Fecal Microbiota Transplantation (FMT) for Treatment of Ulcerative Colitis in Children (External Link)
FMT RECIPIENTS: Participants will be recruited from the patient population treated by the Pediatric Gastroenterology, Hepatology, and Nutrition Section at Baylor College of Medicine/Texas Children's Hospital. I. Activities prior to …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
Morphological Markers of Gastroesophageal Reflux Disease (GERD) (External Link)
This will be a prospective case control study. Children between the ages of 8 and 18 with suspected gastroesophageal reflux disease (GERD) or eosinophilic esophagitis (EoE) based on symptom criteria …
Baylor Role:
Lead Sponsor
Enrolling By Invitation
Defined Fecal Microbiota Transplantation for Clostridium Difficile Diarrhea (External Link)
This study will initially enroll 12 subjects. Based on the relatively large experience with FMT reported to date, we anticipate a prompt and sustained response as determined by a cessation …
Baylor Role:
Lead Sponsor
Terminated
EUS Evaluation of Perianal and Peri-rectal Fistulizing Crohn's Disease With CERTOLIZUMAB Treatment (External Link)
Peri-anal ( located around the anus, the opening of the rectum to the outside of the body) fistulae are a major complication of Crohn's disease and occur in almost 30% …
Baylor Role:
Lead Sponsor
Completed
A Comparison of UGBRS Block and Local Infiltration (External Link)
Laparoscopic appendectomy is a common procedure in pediatric surgery. For single incision laparoscopic appendectomy (SILA), the laparoscope and other instruments are inserted with the aid of a large trocar through …
Baylor Role:
Lead Sponsor
Completed
Delivered Dietary Intervention for Children With Irritable Bowel Syndrome (External Link)
Many children experience stomach pain or discomfort at some point during their lives. Some children have belly discomfort frequently while others rarely have this problem. There have been very few …
Baylor Role:
Lead Sponsor
Completed
Abdominal Symptom Phenotype Study in Children (External Link)
Functional gastrointestinal (GI) disorders (FGIDs), in particular irritable bowel syndrome (IBS) in adults and children, are among the most common and costly health care problems in the US. IBS disproportionately …
Baylor Role:
Lead Sponsor
Completed
Pilot Study Using a Dietary Intervention for Children With Irritable Bowel Syndrome (External Link)
Up to 19% of school-aged children have recurrent abdominal pain (RAP), accounting for 5% of all pediatric office visits and increased morbidity. The majority of children with RAP have irritable …
Baylor Role:
Lead Sponsor
Completed
Safety Study of Probiotics in Adults With Irritable Bowel Syndrome (External Link)
Recent studies performed outside the U.S. and/or prior to recent FDA requirements suggest that the probiotics in VSL#3 may be effective in IBS in adults. Because there is a significant …
Baylor Role:
Lead Sponsor
Withdrawn
Fiber Use in Pediatric Short Bowel Syndrome (External Link)
Short bowel syndrome (SBS) is a form of disease that results from removal of a significant portion of the intestine leading to poor nutrient absorption. Infants with short bowel syndrome …
Baylor Role:
Collaborator