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Addition of Lactobacillus to Metronidazole in Treatment of CDAD (External Link)
Clostridium difficile associated disease (CDAD), which nearly always follows antibiotic therapy, has become increasingly common and important in American hospitals, causing substantial morbidity and mortality. Metronidazole is the recommended treatment …
Baylor Role:
Collaborator
Active, Not Recruiting
A Biologic Validation of Biomarkers of Progressive NEC & Sepsis (External Link)
Necrotizing enterocolitis (NEC) is a severe, sometimes life-threatening inflammation of the intestine that occurs most often in premature babies. If it progresses, the wall of the intestine may perforate, spilling …
Baylor Role:
Collaborator
Completed
Vancomycin vs. Nitazoxanide to Treat Recurrent C. Difficile Colitis (External Link)
Clostridium difficile is the leading cause of nosocomial diarrheal disease associated with antibiotic therapy. This is a debilitating condition with substantial morbidity and a mortality that used to be said …
Baylor Role:
Collaborator
Completed
Fecal Bacterial Flora in Clostridium Difficile-Associated Diarrhea (External Link)
Clostridium difficile associated colitis is an increasing problem in hospitals throughout the developed world; the number of cases has increased, and the failure to respond to conventional therapy has become …
Baylor Role:
Collaborator
Completed
Response of Clostridium Difficile Infection to Metronidazole Therapy (External Link)
Clostridium difficile is a major cause of nosocomial infection. When this organism proliferates in the colon, usually as a result of prior antibiotic therapy in a hospitalized or otherwise debilitated …
Baylor Role:
Collaborator
Completed
Association Between Response to Treatment of C. Diff Colitis and Anti-C.Diff Toxin Antibody (External Link)
Clostridium difficile is the leading cause of nosocomial diarrheal disease associated with antibiotic therapy. This is a debilitating condition with substantial morbidity and mortality that may be around 2-3%. Current …
Baylor Role:
Collaborator
Completed
Compassionate Use of Nitazoxanide for the Treatment of Clostridium Difficile Infection (External Link)
Clostridium difficile is the leading cause of nosocomial diarrheal disease associated with antibiotic therapy. This is a debilitating condition with substantial morbidity and a mortality that may be around 2-3%. …
Baylor Role:
Collaborator
Recruiting
Multi-Center African-American Inflammatory Bowel Disease Study (MAAIS) (External Link)
This current protocol was established as part of an NIDDK initiative to further explore genetic factors associated with IBD. Specifically, the investigators are interested in identifying the genetic, environment and …
Baylor Role:
Collaborator
Completed
Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants (External Link)
PROTOCOL OUTLINE: This is a randomized, double blind study in arms I and II. Patients are randomized to receive either fortified pasteurized donor human milk (arm I) or preterm formula …
Baylor Role:
Collaborator