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19 Results
Recruiting
Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission
This is a pragmatic, open-label, multicenter randomized control trial (RCT) conducted in asymptomatic patients with IBD who have persistent moderate to severe endoscopic inflammation despite optimization of index TIM. This …
Baylor Role: Collaborator
Not Yet Recruiting
RIC-NEC Randomized Controlled Trial
Background: Necrotizing enterocolitis (NEC) is a serious intestinal disease of preterm and term neonates which remains a major cause of intestinal failure, and an unsolved clinical challenge in pediatrics resulting …
Baylor Role: Collaborator
Recruiting
Early Predictors of Necrotizing Enterocolitis in Neonates
The study will enroll premature, low birth weight infants in the Neonatal Intensive Care Units (NICU). Potential study subjects will be identified upon delivery, or transfer to the NICU, and …
Baylor Role: Lead Sponsor
Completed
Metabolomics for Biomarker Discovery in Children With EoE
Eosinophilic esophagitis (EoE) is a disorder of the esophagus triggered by food and/or environmental allergens and is characterized by symptoms of esophageal dysfunction and eosinophilia of the esophagus. The standard …
Baylor Role: Collaborator
Completed
Fecal Microbiota Transplantation (FMT) for Treatment of Ulcerative Colitis in Children
FMT RECIPIENTS: Participants will be recruited from the patient population treated by the Pediatric Gastroenterology, Hepatology, and Nutrition Section at Baylor College of Medicine/Texas Children's Hospital. I. Activities prior to …
Baylor Role: Lead Sponsor
Terminated
Eosinophilic Esophagitis Clinical Therapy Comparison Trial
This study is a open label, randomized, prospective clinical trial comparing the efficacy of a topical steroid preparation to an antigen (food) elimination diet. A total of 40 participants will …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Morphological Markers of Gastroesophageal Reflux Disease (GERD)
This will be a prospective case control study. Children between the ages of 8 and 18 with suspected gastroesophageal reflux disease (GERD) or eosinophilic esophagitis (EoE) based on symptom criteria …
Baylor Role: Lead Sponsor
Enrolling By Invitation
Defined Fecal Microbiota Transplantation for Clostridium Difficile Diarrhea
This study will initially enroll 12 subjects. Based on the relatively large experience with FMT reported to date, we anticipate a prompt and sustained response as determined by a cessation …
Baylor Role: Lead Sponsor
Terminated
EUS Evaluation of Perianal and Peri-rectal Fistulizing Crohn's Disease With CERTOLIZUMAB Treatment
Peri-anal ( located around the anus, the opening of the rectum to the outside of the body) fistulae are a major complication of Crohn's disease and occur in almost 30% …
Baylor Role: Lead Sponsor
Completed
A Comparison of UGBRS Block and Local Infiltration
Laparoscopic appendectomy is a common procedure in pediatric surgery. For single incision laparoscopic appendectomy (SILA), the laparoscope and other instruments are inserted with the aid of a large trocar through …
Baylor Role: Lead Sponsor