Search Clinical Trials
Completed
Safety of Fresolimumab in the Treatment of Osteogenesis Imperfecta (External Link)
Osteogenesis Imperfecta (OI) is a rare disorder that causes bones to break easily. People with OI may have broken bones with little or no trauma, dentinogenesis imperfecta (DI), and, in …
Baylor Role:
Lead Sponsor
Completed
Nitric Oxide Supplementation on Neurocognitive Functions in Patients With ASLD (External Link)
Argininosuccinate lyase deficiency (ASLD; also known as argininosuccinic aciduria) is the second most common urea cycle disorder (UCD) and accounts for 15-20% of all disorders of ureagenesis. Individuals with ASLD …
Baylor Role:
Lead Sponsor
Completed
Fetal Hemoglobin Induction Treatment Metformin (External Link)
This is a dose escalation, pilot study for subjects with sickle cell anemia (SCA) disease to determine if metformin has a beneficial effect on the treatment and quality of life …
Baylor Role:
Lead Sponsor
Completed
Automated Fetal Weight Estimation: A Multicenter Validation Using Fractional Limb Volume (External Link)
Ultrasound has been used for over 20 years to estimate fetal weight prior to birth. Sometimes this estimation is not always similar to what the baby actually weighs. In addition …
Baylor Role:
Lead Sponsor
Completed
'TOTAL' (Tracheal Occlusion To Accelerate Lung Growth) Trial (External Link)
This is a multi-center, non-blinded randomized controlled trial in fetuses with isolated moderate CDH, i.e. moderate lung hypoplasia (as determined by prenatal assessment of lung development). It essentially compares fetal …
Baylor Role:
Collaborator
Completed
Effect of Caudal and Penile Block on Hypospadias Repair Complications (External Link)
Hypospadias is a one of the most common genitourinary (GU) malformations, seen in approximately 1 of 250 male live births, characterized by proximal location of the urethral meatus, dorsal hooded …
Baylor Role:
Lead Sponsor
Completed
Exclusive Human Milk Feeding in Infants With Single Ventricle Physiology (External Link)
This is a single blinded (physician investigator), randomized, controlled trial to evaluate growth velocity and clinical outcomes in infants with single ventricle physiology fed an exclusive human milk diet during …
Baylor Role:
Collaborator
Completed
Fetal 3D Study (Fetal Body Composition and Volumes Study) (External Link)
The NICHD Fetal Growth Study was a multi-site, prospective cohort study designed to establish a standard for normal fetal growth (velocity) and size for gestational age in the U.S. population. …
Baylor Role:
Collaborator
Completed
Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia (External Link)
Participants with Chiari Malformation type I and syringomyelia will be randomized to either have a posterior fossa decompression done with or without duraplasty. The participant will then return to the …
Baylor Role:
Collaborator
Completed
Treatment Alternatives in iSGS (NoAAC PR-02 Study) (External Link)
Idiopathic subglottic stenosis (iSGS) is a rare disease in which the trachea narrows for no known reason. Although uncommon (with an estimated incidence of 1:400,000 persons per year), both the …
Baylor Role:
Collaborator