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Completed
Chemotherapy With or Without Radiation, Low and Intermediate Risk Hodgkins Lymphoma, TXCH-HD-12A (External Link)
At first the subject will have 2 cycles of cancer drugs (Doxorubicin, Bleomycin, Vincristine, Etoposide, Prednisone, Cyclophosphamide). The doctors call this combination of cancer drugs ABVE-PC for short. A cycle …
Baylor Role:
Lead Sponsor
Completed
A Pilot Study to Assess the Glucose Lowering Effect of Metformin and Sitagliptin in Adolescents With Type 1 Diabetes (External Link)
- The study will include a total of 4 visits. The time period between the very first visit and the very last visit will be between 10 and 15 weeks. …
Baylor Role:
Lead Sponsor
Completed
Pilot Clinical Trial of Repeated Doses of Macimorelin to Assess Safety and Efficacy in Patients With Cancer Cachexia (External Link)
The purpose of this study is to evaluate the safety and efficacy of repeated oral administration of macimorelin at different doses daily for 1 week for the treatment of cancer …
Baylor Role:
Collaborator
Completed
Flu-Like Symptoms as a Complication of Botulinum Toxin Therapy (External Link)
Botulinum toxin (BoNT) has become a revolutionary treatment for many neurological, autonomic, gastrointestinal, genitourinary, and cosmetic disorders. The use of this treatment requires expertise in dosage calculations and application technique …
Completed
Study of Dopamine Versus Vasopressin for Treatment of Low Blood Pressure in Low Birth Weight Infants (External Link)
Hypotension in the low birth weight (LBW) and extremely low birth weight (ELBW) infant is often encountered in the postnatal adaptation phase. Severe, prolonged hypotension contributes to cellular dysfunction and …
Baylor Role:
Lead Sponsor
Completed
A Trial of Levodopa in Angelman Syndrome (External Link)
Levodopa is a prodrug that "delivers" dopamine to the brain. It is usually given with carbidopa, a peripheral decarboxylase inhibitor, to increase the bioavailability of levodopa. Animal studies have suggested …
Baylor Role:
Collaborator
Completed
39946-I Laser and Bevacizumab Treatment for Retinopathy of Prematurity (External Link)
This study will enroll preterm infants who were scheduled to receive treatment for ROP by laser or Bevacizumab. We will observe the patients in the hospital for the cure of …
Baylor Role:
Lead Sponsor
Completed
The Management of Glucocorticoid-Induced Hyperglycemia in Hospitalized Patients (External Link)
The target fasting serum glucose (FSG) and pre-meal SG was 90-140 mg/dL, and the random SG was less than 180 mg/dL, taking into consideration the ADA/AACE target glucose levels in …
Baylor Role:
Lead Sponsor
Completed
Role of HIV on Glutathione Synthesis and Oxidative Stress (External Link)
HIV infection is associated the development of increased oxidative stress and deficiency of glutathione (GSH), the dominant endogenous antioxidant protein, but the underlying mechanisms contributing to GSH deficiency are hitherto …
Baylor Role:
Lead Sponsor
Completed
Intranasal Oxytocin and Maternal Neglect (External Link)
The investigators plan to conduct fMRI scanning with a group of mothers who are blindly and randomly assigned either intranasal oxytocin or a placebo. Aim 1: To determine whether intranasal …
Baylor Role:
Lead Sponsor