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Completed
Use of Baxter Animated Retching Faces (BARF) Scale to Measure Nausea in Children Who Speak Spanish
By default the most common objective outcome measure used in pediatric studies has been the incidence and number of emetic episodes. This measure, however, correlates poorly with the somatic subjective …
Baylor Role: Lead Sponsor
Completed
ADXS 11-001 Vaccination Prior to Robotic Surgery, HPV-Positive Oropharyngeal Cancer
This is an investigator-initiated prospective clinical study of patients with stage I-IV squamous cell carcinoma of the oropharynx (OPSCC) who are to undergo ablative transoral robotic surgery (TORS). There is …
Completed
Catheter Biofilm Microbiome in Infected Neonatal Catheters.
Catheter-associated bloodstream infections (CLABSIs) are a significant component of healthcare-associated infections (HAI),which are associated with significant mortality, morbidity and healthcare costs. Neonates are at higher risk for CLABSIs than children …
Baylor Role: Lead Sponsor
Completed
Optimizing Self-Management Adherence and Glycemic Control in Older Teens With Type 1 Diabetes: The Teenwork Study
Glycemic control deteriorates during adolescence as parents become less involved in teens' diabetes management and adherence declines. Thus, there is a need to improve adherence and glycemic control in mid …
Baylor Role: Collaborator
Completed
Transfusional Iron Overload Among Leukemia Survivors
Participants will have blood work drawn after an overnight fast during a routine clinic visit. They will also have an electrocardiogram (EKG) and echocardiogram (ECHO) which are often a required …
Baylor Role: Collaborator
Completed
Continuous Tremor Assessment During Daily Activities
The specific aim of this study is to evaluate if tremor severity and quality of life can be improved more using continuous home monitoring along with traditional assessments versus traditional …
Baylor Role: Collaborator
Completed
Non-invasive Biomarkers of Fibrosis in Pediatric Liver Diseases
Abnormal liver biochemical and function tests are frequently detected in symptomatic patients since many screening blood test panels routinely include them. A population-based survey in the United States conducted between …
Baylor Role: Lead Sponsor
Completed
Novel Dose Escalation to Predict Treatment With Hydroxyurea
To be eligible to participate in this study, patients must have decided that they want to begin hydroxyurea therapy. Patients choosing to participate in this study will be assigned randomly …
Baylor Role: Lead Sponsor
Completed
One-Day Intervention for Depression and Impairment in Migraine Patients
Adults with comorbid depression and migraine will be randomized to a 1-day (6-hour) workshop of Acceptance and Commitment Training + Migraine Education (ACT-ME) or Migraine Education only (MEO). The intervention …
Baylor Role: Lead Sponsor
Completed
Safety and Immunogenicity of the Na-APR-1 Hookworm Vaccine in Healthy Adults
Open-label, dose-escalation phase 1 clinical trial in healthy, hookworm-naïve adults: - Study site: George Washington Medical Faculty Associates, Washington, DC - Number of participants: 40 in 2 cohorts of 20. …
Baylor Role: Lead Sponsor