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Search Clinical Trials
Completed
Vaccine Therapy in Treating Patients With Metastatic, Progressive Prostate Cancer (External Link)
OBJECTIVES: Primary - Evaluate the safety and tolerance of NY-ESO-1/LAGE-1 class-I and class-II vaccine administered subcutaneously in patients with androgen-independent metastatic prostate cancer. Secondary - Compare the response induced by …
Baylor Role:
Lead Sponsor
Completed
Naltrexone and Adrenergic Agents to Reduce Heroin Use in Heroin Addicts (External Link)
Heroin addiction is a serious health problem with no available medical treatment for preventing relapse. Naltrexone is a medication that is currently used to treat substance addiction. It acts by …
Baylor Role:
Lead Sponsor
Completed
Continuous Subcutaneous Infusion of Pramlintide and Insulin (External Link)
The Diabetes Control and Complications Trial (DCCT) showed that improving blood sugar control for individuals with Type 1 diabetes (T1DM) stopped or delayed the onset of long-term health problems. Insulin …
Baylor Role:
Lead Sponsor
Completed
Vancomycin vs. Nitazoxanide to Treat Recurrent C. Difficile Colitis (External Link)
Clostridium difficile is the leading cause of nosocomial diarrheal disease associated with antibiotic therapy. This is a debilitating condition with substantial morbidity and a mortality that used to be said …
Baylor Role:
Collaborator
Completed
Vancomycin vs. Vancomycin Plus Gentamycin in Treatment of MRSA Infection (External Link)
Treatment of bacteremic infection (infection associated with positive blood cultures) due to Staphylococcus aureus has become increasingly problematic as a result of the increasing prevalence of strains that are resistant …
Baylor Role:
Collaborator
Completed
Hemangioma Associated With High Rates of Morbidity (External Link)
Large hemangiomas of the face can be associated with anomalies of the blood vessels of head and chest. The acronym PHACES indicates the association of Posterior fossa and other brain …
Baylor Role:
Collaborator
Completed
Phase 1 Intrathecal Topotecan for Neoplastic Meningitis (External Link)
This is a multi-center, non-randomized pharmacokinetically-guided optimal dosing study of intraventricular topotecan in children with neoplastic meningitis. Topotecan will be administered daily for five consecutive days utilizing the schema shown …
Baylor Role:
Lead Sponsor
Completed
Dexmedetomidine in Pediatric Tonsillectomy (External Link)
Dexmedetomidine, an alpha 2 agonist provides some analgesia without respiratory depression. Children undergoing tonsillectomy and adenoidectomy occasionally have episodes of respiratory obstruction in the recovery room following administration of opioids. …
Baylor Role:
Lead Sponsor
Completed
Response of Clostridium Difficile Infection to Metronidazole Therapy (External Link)
Clostridium difficile is a major cause of nosocomial infection. When this organism proliferates in the colon, usually as a result of prior antibiotic therapy in a hospitalized or otherwise debilitated …
Baylor Role:
Collaborator
Completed
Effect of Curcumin on Lung Inflammation (External Link)
Chronic obstructive pulmonary disease (COPD) and lung cancer are leading causes of death and health care use. Diffuse airways inflammation is seen in COPD and is thought to be the …
Baylor Role:
Lead Sponsor