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Search Clinical Trials
Completed
Biomarker Guided Therapies in Stage A/B Heart Failure (External Link)
Recently the investigators have shown that HF risk prediction can be improved using cardiac troponin T measured with a novel high-sensitivity assay (hs-cTnT) and N-terminal pro-B-type natriuretic peptide (NT-proBNP). Furthermore, …
Baylor Role:
Collaborator
Completed
Safety and Immunogenicity Study of Na-GST-1 With or Without CpG (External Link)
This is a Phase 1 randomized double-blind dose-escalation clinical trial in healthy hookworm-naïve adults conducted at the George Washington Medical Faculty Associates, Washington, DC, and the George Washington University School …
Baylor Role:
Lead Sponsor
Completed
Comparative Efficacy of Phenylbutyrate (PBA) vs. Benzoate in Urea Cycle Disorders (External Link)
The investigators will study and compare how effectively sodium phenylbutyrate, sodium benzoate, and a combination of the two, help excrete nitrogen in healthy volunteers. Subject participation will require three, separate, …
Baylor Role:
Lead Sponsor
Completed
Microbiome Fructan Metabolism and Symptoms in Childhood IBS (External Link)
Fructans (fructo-oligosaccharides) are a type of carbohydrate which can not be hydrolyzed by humans. It is commonly found in wheat in the American diet. After ingestion they arrive essentially intact …
Baylor Role:
Lead Sponsor
Completed
Nitric Oxide Supplementation in Argininosuccinic Aciduria (External Link)
The investigators will perform a double blind, randomized, placebo-controlled, crossover study of NO supplementation in ASA patients assessing endothelial function and blood pressure as primary endpoints, and markers of nitric …
Baylor Role:
Lead Sponsor
Completed
Respiratory Viral Infections in Pediatric Transplantation (External Link)
The purpose of the study is to 1) Determine the incidence of respiratory viral infections diagnosed during the first year post SOT and HSCT; 2a) Determine the all-cause mortality within …
Baylor Role:
Collaborator
Completed
Framingham State Food Study (External Link)
Many overweight and obese people can lose weight for a few months, but most have difficulty maintaining weight loss over the long term. One explanation for the poor long-term outcome …
Baylor Role:
Collaborator
Completed
Promoting The Self-Regulation Of Energy Intake (External Link)
The intervention program was developed and piloted. Expected outcomes: At the end of the intervention program, it is expected that parents in the intervention group will: 1) use more child-centered …
Baylor Role:
Lead Sponsor
Completed
Seattle-PAP Bubble Nasal CPAP and Work of Breathing (External Link)
The primary outcome variable is work of breathing (WOB) over a two hour period, estimated from pressure-rate products, which are assessed with 6 Fr (2 mm) catheters placed in the …
Baylor Role:
Collaborator
Completed
The IMPULSE Study: Pilot (External Link)
Continuous-flow (CF) left ventricular assist devices (LVADs) are an important tool in the treatment of end-stage heart failure, affording patients significantly improved quantity and quality of life. In recent years, …
Baylor Role:
Lead Sponsor