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429 Results

Completed
Novel Offloading for Diabetic Foot Ulcers With PulseFlow: A Prospective Study (External Link)
Diabetic foot ulceration (DFU) is a common and largely preventable complication of diabetes. While most of these ulcers can be treated successfully, some will persist and become infected. Ultimately, nearly …
Baylor Role: Lead Sponsor
Completed
Study of Na-APR-1 (M74)/Alhydrogel® Co-administered With Na-GST-1/Alhydrogel in Brazilian Adults (External Link)
Double blind, randomized, controlled, dose-escalation Phase 1 clinical trial in hookworm exposed adults living in the area of Americaninhas, Minas Gerais, Brazil. Subjects will receive three doses of the assigned …
Baylor Role: Lead Sponsor
Completed
Smart and Secure Children Program for Preschool Obesity (External Link)
Thirty (30) subjects will be enrolled across three (3) TCP clinics where the study will take place. Two types of participants will be recruited for this study: parent participants who …
Baylor Role: Lead Sponsor
Completed
Detection of Exocrine Pancreatic Insufficiency in Patients With Diarrhea and Bloating (External Link)
Exocrine pancreatic insufficiency (EPI) diagnosis can be challenging due to several reasons. First, the main symptoms of EPI such as diarrhea, loose stool, bloating or weight loss have low specificity …
Baylor Role: Lead Sponsor
Completed
Get With the Guidelines in ED Patients With Heart Failure (External Link)
Heart failure (HF) is common and growing healthcare concern. Heart failure affects nearly 6 million Americans. It results in over one million annual hospital discharges as the primary discharge diagnosis …
Baylor Role: Collaborator
Completed
A Study of Transcorporal Versus Standard Artificial Urinary Sphincter Placement (External Link)
The AUS is the gold standard for treatment of severe SUI, particularly in patients following surgical resection of the prostate for prostate cancer. In fact, severe urinary incontinence can be …
Baylor Role: Collaborator
Completed
Treatment Alternatives in iSGS (NoAAC PR-02 Study) (External Link)
Idiopathic subglottic stenosis (iSGS) is a rare disease in which the trachea narrows for no known reason. Although uncommon (with an estimated incidence of 1:400,000 persons per year), both the …
Baylor Role: Collaborator
Completed
Complementary Combination Therapy for Cocaine Dependence (External Link)
During a screening session participants will provide buccal swab for genetics testing, as preliminary data shows that effects of cocaine and of doxazosin are impacted significantly by the genotype at …
Baylor Role: Lead Sponsor
Completed
Individual Blood Pressure Optimization Based on Cerebral Autoregulation After Implantation of Continuous-flow LVAD (External Link)
Preoperative data will be collected as the baseline information through chart review and patient interview before the surgery as follows: patient demographics, co-morbidities, medication, preoperative laboratory results, and preoperative vital …
Baylor Role: Lead Sponsor
Completed
Growth and Microbiome Development in Very Low Birth Weight Infants Fed Primarily Mother's Own Milk vs. Donor Human Milk (External Link)
Background: Human milk feeding provides numerous benefits to preterm infants due to improvements in gastrointestinal maturation, host defense, infection rates, and improved long-term outcomes in neurodevelopment as well as cardiovascular …
Baylor Role: Lead Sponsor