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Left vs Left Randomized Clinical Trial (External Link)
In this prospective, randomized, multi-center clinical trial, the investigators aim to prospectively evaluate the comparative effectiveness His or Left bundle branch pacing (His/LBBP) vs. biventricular pacing (BiVP) in patients with …
Baylor Role:
Lead Sponsor
Recruiting
Accessing Mobility Using Wearable Sensors (External Link)
The investigators specific research questions: (1) Which motor-cognitive parameters measurable by wearable sensors (e.g. gait, balance, frailty index, etc) are linked to specific diseases (e.g. COPD, CHF) (2) Which motor-cognitive …
Baylor Role:
Lead Sponsor
Completed
Get With the Guidelines in ED Patients With Heart Failure (External Link)
Heart failure (HF) is common and growing healthcare concern. Heart failure affects nearly 6 million Americans. It results in over one million annual hospital discharges as the primary discharge diagnosis …
Baylor Role:
Collaborator
Completed
Individual Blood Pressure Optimization Based on Cerebral Autoregulation After Implantation of Continuous-flow LVAD (External Link)
Preoperative data will be collected as the baseline information through chart review and patient interview before the surgery as follows: patient demographics, co-morbidities, medication, preoperative laboratory results, and preoperative vital …
Baylor Role:
Lead Sponsor
Completed
Assessment Of Educational Strategies In Heart Failure Patients Presenting To The Emergency Department For Care (External Link)
In 2015, 12.8% of adults ages 19-64 in the United States lacked any form of health insurance. An even greater number fell under the umbrella of under-insured. Studies indicate that …
Baylor Role:
Lead Sponsor
Completed
Biomarker Guided Therapies in Stage A/B Heart Failure (External Link)
Recently the investigators have shown that HF risk prediction can be improved using cardiac troponin T measured with a novel high-sensitivity assay (hs-cTnT) and N-terminal pro-B-type natriuretic peptide (NT-proBNP). Furthermore, …
Baylor Role:
Collaborator
Completed
The IMPULSE Study: Pilot (External Link)
Continuous-flow (CF) left ventricular assist devices (LVADs) are an important tool in the treatment of end-stage heart failure, affording patients significantly improved quantity and quality of life. In recent years, …
Baylor Role:
Lead Sponsor
Completed
Development & Testing of a Decision Aid for LVAD Placement (External Link)
The goal of this project is to develop a patient-centered decision aid for decision-making about end-stage heart failure treatment. This study seeks to create a decision aid that presents outcomes, …
Baylor Role:
Lead Sponsor
Terminated
Evaluating the Use of Exenatide in People With Type 2 Diabetes and Diastolic Heart Failure (External Link)
Diastolic heart failure is a life-threatening condition that occurs when the ventricles of the heart become stiff and do not fully relax, preventing the heart from properly filling with blood. …
Baylor Role:
Lead Sponsor
Unknown Status
The Cardiovascular Genetic and Therapeutic Implications of Muscular Dystrophy (External Link)
Objective(s) and Hypothesis(es): The objectives to be evaluated are as follows: Specific Hypothesis #1: Heart disease, specifically dilated cardiomyopathy, can be identified early in patients with muscular dystrophy and allow …
Baylor Role:
Lead Sponsor