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Recruiting
Fetal Endotracheal Occlusion (FETO) in the Resolution of Pulmonary Hypertension in Fetuses With Severe CDH (External Link)
Enrollment Women carrying a fetus with severe CDH and a normal karyotype will undergo routine clinical evaluation. The fetus will be 28+0/7 to 31+6/7 weeks of gestational age and have …
Baylor Role:
Collaborator
Unknown Status
Effects of Spironolactone on Collagen Metabolism in Patients With Pulmonary Arterial Hypertension (External Link)
Pulmonary arterial hypertension (PAH) is an orphan disease characterized by pulmonary artery hypertrophy, and resulting vascular remodeling of involved vessels, often leading to right heart failure. Accumulating evidence from vascular …
Baylor Role:
Lead Sponsor
Withdrawn
Pharmacogenomics in Pulmonary Arterial Hypertension (External Link)
This study will make use of a large population of well defined patients with Pulmonary Arterial Hypertension who were enrolled in Encysive Pharmaceutical's STRIDE clinical trials or who have received …
Baylor Role:
Collaborator
Completed
Phase IV Study of Chronic Infusional Epoprostenol for Severe Primary Pulmonary Hypertension (External Link)
PROTOCOL OUTLINE: Patients are treated with a chronic continuous infusion of epoprostenol. The highest tolerated infusion rate is determined for each patient by gradually increasing the rate until the target …
Baylor Role:
Collaborator