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Not Yet Recruiting
Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy Infants (External Link)
The objective of this research protocol is to assess the impacts of genomic sequencing in healthy infants from ethnically and racially diverse communities as part of routine pediatric care. Investigators …
Baylor Role: Collaborator
Not Yet Recruiting
IV Iron Trial for Anemia Related to Uterine Bleeding in Female Patients Presenting to the Emergency Department (External Link)
Iron deficiency anemia (IDA) is the most common hematologic disorder in the United States and worldwide. Patients with moderate to severe anemia often present to the acute care setting for …
Baylor Role: Lead Sponsor
Not Yet Recruiting
A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management (External Link)
The management of pelvic floor overactivity (PFOA) using focal BoNT injection has been gaining clinical interest. Evidence has shown that BoNT injections to the levator ani in patients with CPP …
Baylor Role: Collaborator
Not Yet Recruiting
Pediatric Dose Optimization for Seizures in Emergency Medical Services (External Link)
The Pediatric Dose Optimization for Seizures in Emergency Medical Services (PediDOSE) study is designed to improve how paramedics treat seizures in children on ambulances. Seizures are one of the most …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Pimavanserin for Insomnia in Veterans With Posttraumatic Stress Disorder: Proof of Concept (External Link)
More treatments are needed to target insomnia in Veterans with Posttraumatic Stress Disorder. There is evidence to suggest that pimavanserin, a medication approved by the Food and Drug Administration for …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection (External Link)
The hemolytic uremic syndrome (HUS) is the most serious complication of high-risk Shiga toxin-producing Escherichia coli (STEC) infection and the most common cause of acquired acute kidney injury in otherwise …
Baylor Role: Collaborator
Not Yet Recruiting
Mesenchymal Stem Cells for Age-Related Frailty (External Link)
Frailty is an aging-related syndrome of impaired physiologic reserve and function across multiple organs, leading to increased vulnerability for adverse health outcomes. Frailty is associated with an increased risk for …
Baylor Role: Collaborator
Not Yet Recruiting
Electrical Stimulation for Post Acute COVID-19 Syndrome (External Link)
Postacute COVID-19 syndrome (PACS) is an emerging entity that has been clearly recognized by musculoskeletal pain, fatigue, cognitive, and sleep disturbances, among other symptoms, in patients who have recovered from …
Baylor Role: Lead Sponsor
Not Yet Recruiting
TCR Alpha/Beta and CD19 TCD in HCT for Patients With Hematological Malignancies and Nonmalignant Disorders (External Link)
This is a single arm pilot study of haploidentical HCT (HHCT) with ex vivo TCRαβ+ and CD19+ depletion using the CliniMACS device in patients with hematological malignancies and non-malignant disorders. …
Baylor Role: Lead Sponsor
Not Yet Recruiting
Efficacy of ActiveMatrix on Spinal SSI Rate (External Link)
Postoperative spinal surgical site infections (SSI) have a significant effect on patient morbidity and mortality.1 Spinal SSI as well as other complications including pseudoarthrosis occur at a higher rate in …
Baylor Role: Lead Sponsor