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79 Results
Not Yet Recruiting
Heart Coherence Training on Vascular Ehlers-Danlos Syndrome Patients
Vascular Ehlers Danlos Syndrome (VEDS) is caused by pathogenic variants of the COL3A1 gene, resulting abnormal Type III collagen protein. This impacts the body's connective tissue and makes people with …
Baylor Role: Lead Sponsor
Recruiting
Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion
This is a phase I/II study of haploidentical HCT (HHCT) with ex vivo TCRαβ+ and CD19+ depletion using the CliniMACS device in patients with hematological malignancies and non-malignant disorders. HHCT …
Baylor Role: Lead Sponsor
Recruiting
Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety
Anxiety disorders and posttraumatic stress disorder (PTSD) are among the leading mental health problems in the nation and are highly prevalent among service members and Veterans. The process of recovery …
Baylor Role: Lead Sponsor
Recruiting
Marfan Syndrome Moderate Exercise Trial II
Marfan syndrome (MFS) is a distinctive connective tissue disorder with clinical phenotypes that affect multiple organ systems including the heart, bones, ligaments, and eyes, and are associated with significant risk …
Baylor Role: Lead Sponsor
Withdrawn
Pimavanserin for Insomnia in Veterans With Posttraumatic Stress Disorder: Proof of Concept
More treatments are needed to target insomnia in Veterans with Posttraumatic Stress Disorder. There is evidence to suggest that pimavanserin, a medication approved by the Food and Drug Administration for …
Baylor Role: Lead Sponsor
Recruiting
CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD
Pediatric obsessive-compulsive disorder (OCD) is a common, chronic, and severe psychiatric disorder. Currently, many youth with OCD are treated with medication, such as a serotonin reuptake inhibitor (SRI); however, only …
Baylor Role: Lead Sponsor
Recruiting
Rett Syndrome Registry
The Rett Syndrome Registry is a longitudinal observational study of individuals with MECP2 mutations and a diagnosis of Rett syndrome. Designed together with the IRSF Rett Syndrome Center of Excellence …
Baylor Role: Collaborator
Recruiting
Oxytocin for Hypermobile Ehlers-Danlos Syndrome
This will be a single-site study to evaluate the effect of IV oxytocin on chronic pain in female adult patients with hypermobile EDS. Oxytocin secretion in the body is dynamic …
Baylor Role: Lead Sponsor
Recruiting
Expanding Reach of Evidence-based Psychotherapy for Veterans With Co-occurring Anxiety and Substance Use Disorders.
The current study seeks to better understand how to improve access to evidence-based psychotherapy (EBP) for rural Veterans with co-occurring anxiety and substance use disorders (SUD) using a web-based cognitive …
Baylor Role: Lead Sponsor
Completed
Internet-Based, Parent-Led Cognitive-Behavioral Therapy for Anxiety in Youth With ASD
Autism spectrum disorder, or ASD, is one of the most common neurodevelopmental disorders, affecting up to 1 out of 59 youth in the United States. Anxiety disorders affect 50-80% of …
Baylor Role: Lead Sponsor