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Recruiting
Study of Arginine and Nitric Oxide in Patients With Diabetes (External Link)
Both arginine and its derivative nitric oxide (NO) have been implicated in the regulation of glucose homeostasis. Arginine is a β cell secretagogue, potentiating glucose stimulated insulin secretion. Further, it …
Baylor Role: Lead Sponsor
Recruiting
Comparative Effectiveness of Two Acellular Matrices (Dermacell vs. Integra) for Management of Deep Diabetic Foot Ulcers (External Link)
Diabetes-related foot ulcers (DFUs) are a leading cause of hospitalization and amputation worldwide, and account for 33% of all direct costs of diabetes care in the US. Ulcers requiring acute …
Baylor Role: Lead Sponsor
Recruiting
Strawberry Candy Twists as an Alternative Screen for Gestational Diabetes: A Prospective Trial (External Link)
The aim now is to perform a large, prospective trial to test Twizzlers® as a cost effective glucola alternative in a gravid population to determine its sensitivity, specificity, PPV (positive …
Baylor Role: Lead Sponsor
Recruiting
Fit 24 Technology Intervention YOUTH (External Link)
Hispanic adolescents are disproportionately burdened by obesity and type 2 diabetes compared to non-Hispanic white youth. Disparities in T2D emerge early in life and are driven in part by unhealthy …
Baylor Role: Lead Sponsor
Recruiting
Prospective Study FNB, Is It Time To Abandon Cytological Assessment (External Link)
Endoscopic Ultrasound (EUS) is a minimally invasive procedure used by gastroenterologists to examine pancreatic masses and lesions. A fine needle is traversed through an endoscope and used to acquire tissue …
Baylor Role: Lead Sponsor
Recruiting
Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism (External Link)
After age of 40, testosterone (T) production in men gradually decreases at a rate of 1.6% per year for total and to 2-3% per year for bioavailable T. This reduction …
Baylor Role: Lead Sponsor
Recruiting
EO2 Oxygen Delivery To Study Success Rate of Surgically Closed Wounds (External Link)
Surgical wound (e.g., post minor amputation, reconstruction surgery, or surgical incision) complications such as infection, dehiscence, necrotic tissue, surgical revision, and poor cosmesis are unfortunately highly prevalent in patients undergoing …
Baylor Role: Lead Sponsor
Recruiting
Smart Boot Use to Measure Offloading Adherence (External Link)
The purpose of this study is to help people with diabetes who develop neuropathic diabetic foot ulcers (DFUs). These ulcers, or sores, if left untreated can increase the chance of …
Baylor Role: Collaborator
Recruiting
BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes (External Link)
Type 2 diabetes is an increasingly common disease that affects more than 10 percent of adults in the United States. Multiple medications are available to treat this condition. However, many …
Baylor Role: Collaborator