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16 Results

Terminated
Allogeneic SCT Of Pts With SCID And Other Primary Immunodeficiency Disorders (External Link)
Donor Stem Cell Processing for Mismatched Donors: Harvested peripheral blood stem cells will be enriched for CD34 cells using the CliniMACS CD34 Reagent system, according to Center for Cell and …
Baylor Role: Lead Sponsor
Terminated
Treatment of Hemoglobin SC Disease With Hydroxyurea (External Link)
To be eligible to participate in this study, patients must have HbSC disease, have experienced a sickle cell disease related complication, or have a score of 80 or lower on …
Baylor Role: Lead Sponsor
Terminated
Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF) (External Link)
The STAR-too study is a randomized, open label, multi-center study in CF patients with new MRSA isolated from the respiratory tract (sputum or oropharyngeal (OP) swab). The purpose of the …
Baylor Role: Collaborator
Terminated
Treatment of Adult Patients With Hemoglobin SC Disease (SCYTHE) (External Link)
Patients will be recruited from the patient population followed at the Texas Children's Cancer and Hematology Centers (TCC/HC)/Baylor College of Medicine (BCM) and the University of Texas Houston Hematology Center. …
Baylor Role: Lead Sponsor
Terminated
Randomized Clinical Trial of Early Delivery in Fetal Gastroschisis vs. Routine Care (External Link)
Gastroschisis is a congenital malformation in which abdominal organs protrude through an abdominal wall defect, leading to considerable morbidity and mortality during infancy. In contrast to the second class of …
Baylor Role: Lead Sponsor
Terminated
Transcranial Doppler (TCD) With Transfusions Changing to Hydroxyurea (External Link)
Despite the clear results of the STOP and the follow-up STOP II trials, the use of chronic erythrocyte transfusions for primary stroke prevention in children with Sickle Cell Anemia (SCA) …
Baylor Role: Collaborator
Terminated
Use of Rft5-Dga to Deplete Alloreactive Cells for Pts With Fanconi Anemia After Haploidentical SCT (External Link)
Patients will have received a haplo-identical stem cell transplant on our on-going study "CD45 (YTH-24 and YTH-54) and CD52 (Campath 1H) Monoclonal Antibody Conditioning Regimen for Allogeneic Donor Stem Cell …
Baylor Role: Lead Sponsor
Terminated
Open Myelomeningocele Repair With High Maternal BMI (External Link)
The research will be conducted at the following location(s): Baylor College of Medicine and Texas Children's Hospital- Women's Pavilion. About 15 subjects will be enrolled in this study. In order …
Baylor Role: Lead Sponsor
Terminated
Steroid Treatment for Sickle Cell Pain Crisis (External Link)
In the United States, 9% of African Americans have sickle cell trait and 1 in 600 has sickle cell disease. Vaso- occlusive crises in sickle cell disease remain a frequent …
Baylor Role: Lead Sponsor
Terminated
Oral Magnesium Pidolate, Hemoglobin SC Disease, MG Pidolate (External Link)
This is a placebo-controlled study which means that the effectiveness of the magnesium medication (the chemical form of which is known as Mg pidolate) will be compared to placebo. A …
Baylor Role: Lead Sponsor