Search Clinical Trials

124 Results

Recruiting
Genetic Disorders of Obesity Program Database (External Link)
Children and adolescents who have suffered from severe weight gain prior to 5 years of age and who are seen in the Genetic Disorders of Obesity Program at Texas Children …
Baylor Role: Lead Sponsor
Recruiting
Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome (External Link)
Investigators will measure pre-determined biomarkers with known or suspected association with ARDS severity or outcome. Simultaneously, investigators will measure gene expression of peripheral blood. Both plasma biomarkers and gene expression …
Baylor Role: Collaborator
Recruiting
Clinical and Basic Investigations Into Congenital Disorders of Glycosylation (External Link)
The investigators are conducting a natural history study of patients with congenital disorders of glycosylation (CDG). The study will look into the progression of the disease amongst the participants and …
Baylor Role: Collaborator
Recruiting
Fetal Endotracheal Occlusion (FETO) in the Resolution of Pulmonary Hypertension in Fetuses With Severe CDH (External Link)
Enrollment Women carrying a fetus with severe CDH and a normal karyotype will undergo routine clinical evaluation. The fetus will be 28+0/7 to 31+6/7 weeks of gestational age and have …
Baylor Role: Collaborator
Recruiting
Prenatal Genetic Diagnosis by Genomic Sequencing (External Link)
Whole exome and whole genome sequencing (WGS) have expanded the ability to determine the genetic etiology of previously undiagnosed disorders. This study is a multicenter prospective cohort study to evaluate …
Baylor Role: Collaborator
Active, Not Recruiting
Patch vs. No Patch Fetoscopic Meningomyelocele Repair Study (External Link)
Spina bifida can be a devastating neurological congenital anomaly. It results from incomplete closure of the neural tube between 22 and 28 embryological days. Its incidence is approximately 1-2 per …
Baylor Role: Lead Sponsor
Completed
Pimavanserin Treatment in TS (External Link)
Tourette Syndrome is typically treated with drugs that block or reduce the function of dopamine (a brain chemical involved in movement). However, many of these drugs have adverse effects including …
Completed
Assessment of a PERT-free Nutritional Therapeutic Delivery System for Cystic Fibrosis (External Link)
This is a single center, randomized, double-blind, cross-over trial (with a follow-on single-blind safety evaluation stage), assessing a ready-to-drink nutritional supplement used without PERT ("PERT-free"), nutritional supplement for blood lipid …
Baylor Role: Collaborator
Terminated
Open Myelomeningocele Repair With High Maternal BMI (External Link)
The research will be conducted at the following location(s): Baylor College of Medicine and Texas Children's Hospital- Women's Pavilion. About 15 subjects will be enrolled in this study. In order …
Baylor Role: Lead Sponsor
Active, Not Recruiting
N-Acetylcysteine in Biliary Atresia After Kasai Portoenterostomy (External Link)
Biliary atresia (BA) is a disease characterized by fibro-obliteration of extrahepatic bile ducts leading to impaired bile flow (Sokol et al., 2007). BA is treated with the Kasai portoenterostomy (KP), …
Baylor Role: Lead Sponsor