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Nitric Oxide During CPB to Reduce AKI in Neonates (External Link)
Screening: All patients undergoing either elective or emergency cardiac surgery will be screened against the eligibility criteria. Research Sample Collection: Blood and urine will be collected for the first 48 …
Recruiting
L-Citrulline Dose Finding Safety Study in MELAS (External Link)
The human body is made of many cells and each cell contains many mitochondria. Mitochondria are called the powerhouses of the cell, because they produce the energy needed for a …
Baylor Role:
Lead Sponsor
Completed
Study of Arginine and Nitric Oxide in Patients With Diabetes (External Link)
Both arginine and its derivative nitric oxide (NO) have been implicated in the regulation of glucose homeostasis. Arginine is a β cell secretagogue, potentiating glucose stimulated insulin secretion. Further, it …
Baylor Role:
Lead Sponsor
Completed
Nitric Oxide Supplementation on Neurocognitive Functions in Patients With ASLD (External Link)
Argininosuccinate lyase deficiency (ASLD; also known as argininosuccinic aciduria) is the second most common urea cycle disorder (UCD) and accounts for 15-20% of all disorders of ureagenesis. Individuals with ASLD …
Baylor Role:
Lead Sponsor
Completed
Non Invasive Oral Cancer Screening Among HIV Infected Individuals (External Link)
If you agree to take part in this study, you will be asked to come to the clinic for 2 study visits. First Study Visit: - You will be asked …
Baylor Role:
Collaborator
Withdrawn
Trial- Dysphagia From ETT or GI Endoscopy (External Link)
Patients between the ages of 5-17 with normal cognitive function presenting for Upper GI endoscopy will be considered for participation in this study. After consent is obtained from the parent/legal …
Baylor Role:
Lead Sponsor
Completed
Nitric Oxide Supplementation in Argininosuccinic Aciduria (External Link)
The investigators will perform a double blind, randomized, placebo-controlled, crossover study of NO supplementation in ASA patients assessing endothelial function and blood pressure as primary endpoints, and markers of nitric …
Baylor Role:
Lead Sponsor
Completed
Nitric Oxide Flux and Ureagenesis in Argininosuccinate Synthetase Deficiency (ASSD)(Citrullinemia I) (External Link)
This is an interventional, case control study to investigate the production of nitric oxide in patients with citrullinemia type I. Through the infusion of isotopes [15N2-ureido] arginine, [5-13C,4, 4, 5, …
Baylor Role:
Lead Sponsor
Completed
Nitric Oxide Production in MELAS Syndrome (External Link)
What does the study involve? Individuals with MELAS syndrome will be admitted twice to the General Clinical Research Center (GCRC) at Texas Children's Hospital. Each time they will stay for …
Baylor Role:
Lead Sponsor
Completed
Prevention of Recurrent Infections Caused by Community Acquired Staphylococcus Aureus (CA-SA) in Children (External Link)
In many areas of the United States, methicillin-resistant Staphylococcus aureus is now an established community pathogen (CA-MRSA). At Texas Children's Hospital (TCH), about 75% of S. aureus isolates recovered from …
Baylor Role:
Lead Sponsor