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29 Results
Completed
Effect of Opioids on Ventilation in Children With Obstructive Sleep Apnea
Ventilatory suppression in children following opioid administration is of obvious concern, especially following routine surgical procedures (i.e. adenotonsillectomy). It is thought that patients with obstructive sleep apnea (OSA) have increased …
Baylor Role: Lead Sponsor
Completed
Effect of Monochromatic Light on Incidence of Emergence Delirium in Children
Emergence delirium/emergence agitation (ED/EA) is a behavioral phenomenon of unclear etiology consisting of short lived behavioral changes that can be both traumatic to families and pose a safety risk to …
Baylor Role: Lead Sponsor
Completed
Review of Diagnostic Yield of MRI Brain Results in Children Under Age 3 Years
On December 14, 2016 the FDA issued a warning regarding elective anesthetics in children under three years of age. While a single, short exposure to general anesthesia may not have …
Baylor Role: Lead Sponsor
Completed
Effect of Caudal and Penile Block on Hypospadias Repair Complications
Hypospadias is a one of the most common genitourinary (GU) malformations, seen in approximately 1 of 250 male live births, characterized by proximal location of the urethral meatus, dorsal hooded …
Baylor Role: Lead Sponsor
Completed
Aromatase Inhibitors and Weight Loss in Severely Obese Hypogonadal Male Veterans (Pilot)
After the age of 40, testosterone (T) production in men gradually decreases at a rate of 1.6% per year for total and to 2-3% per year for bioavailable T. Because …
Baylor Role: Lead Sponsor
Completed
Fast-Fail Trials in Mood and Anxiety Spectrum Disorders; Kappa Opioid Receptor Phase 2a
FAST-MAS addresses an important problem and critical barrier to progress in Mood and Anxiety Spectrum Disorders and if the aims of the project are achieved, FAST-MAS could shift scientific knowledge, …
Baylor Role: Collaborator
Completed
Peanut Oral Immunotherapy in Children With Peanut Allergy (Peanut Flour)
This is a phase I, open label study for the initial 12 month desensitization phase of peanut oral immunotherapy and a 2 year maintenance phase. Subjects will be recruited to …
Baylor Role: Lead Sponsor
Completed
Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse
The noradrenergic system, especially the alpha 1-adrenergic receptor, may play an important role in cocaine addiction in humans. Doxazosin is a long-acting and selective alpha 1-adrenergic receptor blocker, which inhibits …
Baylor Role: Collaborator
Completed
Bicuspid Valve Aortopathy Feasibility Study
The study will consider all patients with a bicuspid aortic valve and 1) determine the number of patients needed to be screened for a clinical trial, based on patient eligibility …
Baylor Role: Collaborator
Completed
Encapsulated Calcium Absorption in Pregnancy
This study will enroll at least 60 pregnant women in a randomized cross-over study in Dhaka, Bangladesh. Each participant will be randomized to one of 3 calcium doses: 500 mg, …
Baylor Role: Collaborator