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6 Results

Not Yet Recruiting
A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management (External Link)
The management of pelvic floor overactivity (PFOA) using focal BoNT injection has been gaining clinical interest. Evidence has shown that BoNT injections to the levator ani in patients with CPP …
Baylor Role: Collaborator
Unknown Status
OnabotulinumtoxinA (onaBoNT-A) Versus Oral Oxybutynin ER (External Link)
Current treatment of neurogenic bladder dysfunction (NGB) is limited by the suboptimal results achieved using standard antimuscarinic agents. A prominent role for the actions of alternative transmitters/growth factors in peripheral …
Completed
Flu-Like Symptoms as a Complication of Botulinum Toxin Therapy (External Link)
Botulinum toxin (BoNT) has become a revolutionary treatment for many neurological, autonomic, gastrointestinal, genitourinary, and cosmetic disorders. The use of this treatment requires expertise in dosage calculations and application technique …
Completed
H-22411: BOTOX® for Peyronie's Disease (External Link)
Treatments for this disease have been limited and often unsuccessful. The goal of treatment is to reduce pain and maintain sexual function. Oral medicines that prevent plaque formation and promote …
Completed
Study of the Safety and Efficacy of Botox in Bruxism (External Link)
Bruxism represents involuntary movements of the jaw muscles, resulting in tooth grinding and clenching. Generally it occurs during sleep, but occasionally can be present during the day, so called awake …
Baylor Role: Lead Sponsor
Terminated
Botox-A Injection to Improve Bladder Function in Early Spinal Cord Injury (#H-20344) (External Link)
Approximately 10,000 spinal cord injuries (SCI) occur each year, most of which occur in males (80%). Many of these patients develop neurogenic bladder dysfunction (NGB) characterized by overactivity of the …
Baylor Role: Lead Sponsor