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8 Results
Recruiting
Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease
Glutathione (GSH) deficiency, oxidative stress, mitochondrial dysfunction, insulin resistance and inflammation are linked to Alzheimer's disease (AD). In prior studies, investigators have shown that GSH deficiency contributes to mitochondrial impairment …
Baylor Role: Lead Sponsor
Recruiting
Glycine "Deficiency" and the Kinetics of Acylglycine in Morbid Obesity
This study aims to evaluate the effects of oral glycine supplementation on plasma glycine concentration, intracellular glutathione (GSH) concentration, plasma acylglycine concentration, urine acylglycine concentration, and insulin resistance in subjects …
Baylor Role: Collaborator
Active, Not Recruiting
Glutathione, Oxidative Stress and Mitochondrial Function in COVID-19
This study will investigate associated defects in the following two populations of patients with COVID-19: Hospitalized patients admitted for COVID-19 will sign an informed consent form, and be randomized to …
Baylor Role: Lead Sponsor
Recruiting
Glutathione in Mild Cognitive Impairment
Subjects with MCI will be recruited by written informed consent using forms approved by the Baylor IRB. Subjects will stop nonvitamin supplements for 4wks before screening labs (blood count, HbA1c, …
Baylor Role: Lead Sponsor
Completed
Energetics and Function in Older Humans
Data not available at present
Baylor Role: Lead Sponsor
Completed
Glutathione and Function in HIV Patients
Detailed data are not as yet available
Baylor Role: Lead Sponsor
Completed
Glutathione and Fuel Oxidation in Aging
Subjects will be recruited by written informed consent on forms approved by the Institutional Review Board of Baylor College of Medicine at the time of approval of the full protocol. …
Completed
Role of HIV on Glutathione Synthesis and Oxidative Stress
HIV infection is associated the development of increased oxidative stress and deficiency of glutathione (GSH), the dominant endogenous antioxidant protein, but the underlying mechanisms contributing to GSH deficiency are hitherto …
Baylor Role: Lead Sponsor