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15 Results

Terminated
On-Q Pump vs Epidural for Postoperative Pain Control in Children (External Link)
The study design is a randomized, controlled trial to compare the effectiveness of on-q pump subcutaneous incisional analgesia to epidural analgesia for postoperative pain relief in children undergoing open abdominal, …
Baylor Role: Lead Sponsor
Terminated
Effect of Dapagliflozin on Inflammation and Endothelial Function (External Link)
The insulin-resistant state of type 2 diabetes mellitus (T2DM) is largely mediated by inflammatory pathways affecting skeletal muscle which is the primary site of whole body insulin resistance. Nuclear factor …
Baylor Role: Lead Sponsor
Terminated
Sertraline in Treatment of Low-Risk Myelodysplastic Syndrome (External Link)
This pilot study investigates clinical benefit of four 28-day cycles of sertraline in low-risk MDS patients. Participants will receive 100mg of oral sertraline daily. The study will also evaluate potential …
Baylor Role: Collaborator
Terminated
Intravenous Ketamine in the Treatment of Obsessive-Compulsive Disorder (External Link)
This study will test the safety and efficacy of a single intravenous (IV) dose of the N-methyl-D-aspartate (NMDA) glutamate receptor antagonist, ketamine, in treatment-resistant OCD.
Terminated
Effect of Saxagliptin Treatment on Myocardial Fat Content, and Monocyte Inflammation (External Link)
Obese, insulin resistant individuals have an excess of fat in the liver which is not attributable to alcohol or other known causes of liver disease, a condition defined as nonalcoholic …
Baylor Role: Lead Sponsor
Terminated
Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia (External Link)
Satisfactory pain control can generally be achieved after major surgery of the tibia through a combination of enteral and parenteral medications, neuraxial techniques (such as epidural analgesia), and/or regional techniques …
Baylor Role: Lead Sponsor
Terminated
Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF) (External Link)
The STAR-too study is a randomized, open label, multi-center study in CF patients with new MRSA isolated from the respiratory tract (sputum or oropharyngeal (OP) swab). The purpose of the …
Baylor Role: Collaborator
Terminated
Genetic Susceptibility to Kidney Cancer (External Link)
This study will further the understanding of the genetic events leading to the development of RCC; explore the genetic basis for genetic instability and how it affects cancer risk; and …
Baylor Role: Lead Sponsor
Terminated
Physiological Disturbances Associated With Neonatal Intraventricular Hemorrhage (External Link)
Annually, almost 5,000 extremely low birth weight (9 ounces to about 2 lbs) infants born in the US survive with severe bleeding in the brain (intraventricular hemorrhage); this devastating complication …
Baylor Role: Lead Sponsor
Terminated
Allogeneic SCT Of Pts With SCID And Other Primary Immunodeficiency Disorders (External Link)
Donor Stem Cell Processing for Mismatched Donors: Harvested peripheral blood stem cells will be enriched for CD34 cells using the CliniMACS CD34 Reagent system, according to Center for Cell and …
Baylor Role: Lead Sponsor