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Terminated
Ketamine in Veterans With Gulf War Illness (External Link)
Recruitment for this study starts after protocol approval by the BCM IRB, MEDVAMC R&D, and DoD HRPO. All study procedures are for research only. Potential subjects will be recruited (i) …
Baylor Role:
Lead Sponsor
Terminated
Sertraline in Treatment of Low-Risk Myelodysplastic Syndrome (External Link)
This pilot study investigates clinical benefit of four 28-day cycles of sertraline in low-risk MDS patients. Participants will receive 100mg of oral sertraline daily. The study will also evaluate potential …
Baylor Role:
Collaborator
Terminated
Intravenous Ketamine in the Treatment of Obsessive-Compulsive Disorder (External Link)
This study will test the safety and efficacy of a single intravenous (IV) dose of the N-methyl-D-aspartate (NMDA) glutamate receptor antagonist, ketamine, in treatment-resistant OCD.
Terminated
Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF) (External Link)
The STAR-too study is a randomized, open label, multi-center study in CF patients with new MRSA isolated from the respiratory tract (sputum or oropharyngeal (OP) swab). The purpose of the …
Baylor Role:
Collaborator
Terminated
T-Reg Cell Kinetics, Stem Cell Transplant, REGALE (External Link)
To participate in this transplant, the patient will need to have a central line. Before the transplant we will test the blood for viruses which can cause problems after the …
Baylor Role:
Lead Sponsor
Terminated
T-Regulatory Cell Kinetics, Stem Cell Transplantation, REGKINE (External Link)
Before the transplant we will test the patients blood for viruses which can cause problems after the transplant. These viruses include Hepatitis B, (which causes liver damage), cytomegalovirus, (which causes …
Baylor Role:
Lead Sponsor
Terminated
Reduced Intensity Preparative Regimen Followed by Stem Cell Transplant (FAB) (External Link)
Allogeneic stem cell transplantation with high-dose chemotherapy affords a better chance of cure of malignant and non-malignant hematological diseases compared to autologous transplantation, because of the lack of stem cell …
Baylor Role:
Lead Sponsor
Terminated
Bone Marrow Transplantation, Hemoglobinopathies, SCALLOP (External Link)
Prior to any bone marrow transplant, we will need patients to: - Answer questions about their medical history; - Undergo a physical examination; - Have tests done to see how …
Baylor Role:
Collaborator
Terminated
Allogeneic Stem Cell Transplantation, Severe Homzygous 0/+Thalassemia or Sever Variants of Beta 0/+ Thalassemia, THALLO (External Link)
To be treated on this study, we will test the blood to check for viruses, including HIV (the virus that causes AIDS). If the HIV test is positive, a transplant …
Baylor Role:
Lead Sponsor
Terminated
Allogeneic Stem Cell Transplant for Patients With Severe Aplastic Anemia (External Link)
Before patients receive any treatments, they will have the following: - Complete history and physical exam - Dental consultation - Bone marrow aspirate - Blood tests - Urinanalysis - Tests …
Baylor Role:
Lead Sponsor