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Recruiting
National Liver Cancer Screening Trial (External Link)
The TRACER phase IV biomarker study is a randomized trial comparing ultrasound-based screening versus a biomarker-based strategy in patients with cirrhosis. In brief, 5500 patients with cirrhosis from any etiology …
Baylor Role:
Collaborator
Recruiting
Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion (External Link)
This is a phase I/II study of haploidentical HCT (HHCT) with ex vivo TCRαβ+ and CD19+ depletion using the CliniMACS device in patients with hematological malignancies and non-malignant disorders. HHCT …
Baylor Role:
Lead Sponsor
Recruiting
Traction vs. No Traction in Colonic ESD (External Link)
Endoscopic submucosal dissection (ESD) is the mainstay for the treatment of complex colorectal polyps particularly those with a higher risk of superficial submucosal invasion. However, colonic ESD is technically difficult …
Baylor Role:
Lead Sponsor
Recruiting
Emergency Room HPV Self-Sampling Study (ACT NOW) (External Link)
The goal of this study is to develop and evaluate an evidence-based public health intervention using HPV self-sampling approach in an opportunistic setting to increase cervical cancer screening among screening …
Baylor Role:
Lead Sponsor
Recruiting
Survivorship Care for Women Living With Ovarian Cancer: (POSTCARE-O) (External Link)
Study Design We will conduct a 2-arm randomized controlled trial to evaluate the impact of a telehealth delivered survivorship transition care process. Ovarian cancer survivors (120) will be randomly allocated …
Baylor Role:
Lead Sponsor
Recruiting
Topical Dermaprazole for Radiation Dermatitis in Breast Cancer and Head and Neck Cancer Patients (TOPAZ) (External Link)
For this study, patients will be stratified into one of the following two arms: 1) head and neck or 2) breast cancer. All study participants will begin using Dermaprazole for …
Recruiting
Systematic Light Exposure in Pediatric Brain Tumor Survivors (External Link)
Participants will be randomized to take part in one of two groups: 1. The Bright Light Group will be exposed to bright light (1,000 lux at eye level) using light …
Baylor Role:
Lead Sponsor
Recruiting
Improving Comprehensive Care of Cancer Patients (External Link)
Design Overview. This is a randomized controlled trial of a consecutive sample of 300 medically underserved breast, GI, and hematological cancer patients with comorbidities recruited from Harris Health Ben Taub …
Baylor Role:
Lead Sponsor
Recruiting
Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors (External Link)
Approximately 15-24 subjects will participate in the treatment part of this study. Maximum of 180 mL of blood (not exceeding 3ml/kg/day) is collected from patients to grow the T cells …
Baylor Role:
Lead Sponsor
Recruiting
Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors (External Link)
Approximately 118-27 subjects will participate in the treatment part of this study. Maximum of 180 mL of blood (approximately 12 tablespoons) is collected from patients to grow the T cells …
Baylor Role:
Lead Sponsor