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Traction vs. No Traction in Colonic ESD (External Link)
Endoscopic submucosal dissection (ESD) is the mainstay for the treatment of complex colorectal polyps particularly those with a higher risk of superficial submucosal invasion. However, colonic ESD is technically difficult …
Baylor Role:
Lead Sponsor
Recruiting
Establishing a Pediatric Reference Range for the 13C-Spirulina Gastric Emptying Breath Test (GEBT) (External Link)
Children will complete questionnaires to ensure that they are qualified to enter the study and are likely to have normal gastric emptying rates. Informed consent/assent will be obtained. Breath samples …
Baylor Role:
Collaborator
Recruiting
HR-EGG in Medically Refractory Gastroparesis (External Link)
Gastroparesis is a chronic digestive disorder defined by the symptoms of nausea, vomiting, bloating, and abdominal pain in the setting of objectively delayed gastric emptying without mechanical gastric outlet obstruction. …
Baylor Role:
Collaborator
Recruiting
Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission (External Link)
This is a pragmatic, open-label, multicenter randomized control trial (RCT) conducted in asymptomatic patients with IBD who have persistent moderate to severe endoscopic inflammation despite optimization of index TIM. This …
Baylor Role:
Collaborator
Recruiting
Improving Comprehensive Care of Cancer Patients (External Link)
Design Overview. This is a randomized controlled trial of a consecutive sample of 300 medically underserved breast, GI, and hematological cancer patients with comorbidities recruited from Harris Health Ben Taub …
Baylor Role:
Lead Sponsor
Recruiting
Do Biomarkers Predict Response to a Pediatric Chronic Pain Symptom Management Program? (External Link)
AIM 1: We will categorize children ages 7-12 yrs. of age with FGIDs (n=250) as to whether they have/do not have one or more of the following abnormal physiologic changes: …
Baylor Role:
Lead Sponsor
Recruiting
Pediatric Gastroparesis Registry (External Link)
In the Pediatric Gastroparesis Registry (PGpR), we will collect detailed epidemiological, clinical, psychological, and patient outcome data with the goal of classifying patients with gastroparesis and gastroparesis-like syndromes into pathophysiologically …
Baylor Role:
Collaborator
Recruiting
Early Predictors of Necrotizing Enterocolitis in Neonates (External Link)
The study will enroll premature, low birth weight infants in the Neonatal Intensive Care Units (NICU). Potential study subjects will be identified upon delivery, or transfer to the NICU, and …
Baylor Role:
Lead Sponsor
Recruiting
Pediatric Acute Gastrointestinal Bleeding Registry (External Link)
A. Specific Aims/Objectives: The goal of this study is to identify significant clinical and laboratory risk factors in pediatric patients with significant upper gastrointestinal bleeding. This is defined as bleeding …
Baylor Role:
Collaborator
Recruiting
Accuracy, Yield and Clinical Impact of a Low-Cost HRME in the Early Diagnosis of Esophageal Adenocarcinoma (External Link)
Primary outcomes: - the diagnostic yield (defined as the proportion of mucosal biopsy samples with neoplasia) of HRME with directed biopsy - compared to standard white-light endoscopy with 4-quadrant random …
Baylor Role:
Collaborator