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Completed
VA Home-Based Emotional Learning With Practical Skills (External Link)
VA-HELPS will include flexibility in both content and delivery to meet the needs of Home Based Primary Care (HBPC) Veterans. Content will be modular to meet the needs of both …
Baylor Role:
Lead Sponsor
Completed
Calmer Life: Testing the Effectiveness of a Treatment for Anxiety (External Link)
Cognitive behavioral treatment (CBT) produces positive outcomes for late-life worry/GAD in academic and primary care settings, but minorities are significantly underrepresented in clinical trials, and standard CBT poorly addresses the …
Baylor Role:
Lead Sponsor
Completed
Pramipexole as a Treatment for Cocaine Dependence (External Link)
In this protocol we propose to assess the impact of treatment with higher doses of the potent D2/3 agonist pramipexole, using the extended release preparation that has been shown to …
Baylor Role:
Lead Sponsor
Completed
Exercise as a Behavioral Treatment for Cocaine Dependence (External Link)
This proposal represents an important research effort with considerable public health significance in that it will provide detailed behavioral and physiological data for a non-pharmacological intervention to treat stimulant addiction. …
Baylor Role:
Lead Sponsor
Completed
A Pilot Study of Cabergoline for the Treatment of Cocaine Dependence (External Link)
Secondary aims are to clarify the genetics of substance abuse, potentially leading to improved methods to diagnosis those at risk and to help develop better therapeutic interventions and to develop …
Baylor Role:
Lead Sponsor
Completed
Doxazosin for Psychostimulant Dependence (External Link)
Psychostimulant dependence is a major public health problem and no medications have been shown to be very effective in treating this disorder. Thus, the investigators wish to study whether a …
Baylor Role:
Collaborator
Completed
Sleep Abnormalities in Rare Genetic Disorders: AS, RTT, and PW (External Link)
Subjects with AS, RTT or PWS and normal siblings (controls) will be recruited for study participation. Subjects will be recruited from the Rare Disease Clinical Research Network (RDCRN) consortium registries …
Baylor Role:
Lead Sponsor
Completed
DOX as a Potential Treatment for Methamphetamine Dependence (External Link)
Purpose: To determine the effects of treatment with doxazosin, compared to treatment with placebo, on methamphetamine-induced craving and subjective effects in methamphetamine-dependent human volunteers. Secondary aims are to clarify the …
Baylor Role:
Lead Sponsor
Completed
Varenicline as a Treatment for Methamphetamine Dependence (External Link)
This study is part of an effort to develop treatments for methamphetamine abuse. Varenicline is a drug that changes levels of certain brain chemicals that may also be useful in …
Baylor Role:
Lead Sponsor
Completed
Carvedilol for Psychostimulant Dependence (External Link)
This study examines whether carvedilol prolongs abstinence in recently abstinent cocaine dependent participants.
Baylor Role:
Collaborator