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Completed
Pancreas Resection With and Without Drains (External Link)
The rate of pancreatic fistula after pancreas resection is about 10% and surgeons have traditionally placed drains near the pancreatic anastomosis to control this potentially very serious complication. In recent …
Baylor Role:
Lead Sponsor
Completed
Umbilical Cord Blood Transplant for Children With Myeloid Hematological Malignancies (External Link)
The following will be given as the conditioning regimen for the transplant: BUSULFAN: Busulfan (intravenous BUSULFEX) dosing will be as follows: patients <12 kg: 1.1 mg/kg/dose IV every 6 hours …
Baylor Role:
Lead Sponsor
Completed
CMV-specific Cytotoxic T Lymphocytes Expressing CAR Targeting HER2 in Patients With GBM (External Link)
When the patient enrolls on this study, they will be assigned to a dose of HER2-CAR CMV-T cells. The patient will be given a single injection of cells into the …
Baylor Role:
Lead Sponsor
Completed
Carboplatin and Docetaxel Followed by Epstein-Barr Virus Cytotoxic T Lymphocytes (External Link)
A blood sample will be obtained to start making the CTLs before the patient begins chemotherapy. The patients EBV-specific T cells will be grown while the patient is being treated …
Baylor Role:
Lead Sponsor
Completed
Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma (External Link)
With the exception of patients with diffuse intrinsic pontine glioma (DIPG), all patients should have the maximal surgical resection that can be safely performed prior to study entry. Submission of …
Baylor Role:
Lead Sponsor
Completed
Her2 and TGFBeta Cytotoxic T Cells in Treatment of Her2 Positive Malignancy (External Link)
The patient will give blood to grow T cells on either one to two separate occasions. Then, the EBV-specific T cells will be made. These cells will be grown and …
Baylor Role:
Lead Sponsor
Completed
Prostate Cancer Symptom Management for Low Literacy Men (External Link)
Prostate cancer has recently surpassed lung cancer to become the most common cancer of American men. The estimated number of new prostate cancer cases in 2005 is expected to be …
Baylor Role:
Lead Sponsor
Completed
MTD Study of Vaccine BP-GMAX-CD1 Plus AP1903 to Treat Castrate Resistant Prostate Cancer (External Link)
Patients will be screened within 6 weeks prior to Week 1. A total of 3 cohorts, consisting of 3 to 6 patients each, are planned to receive five to eight …
Baylor Role:
Collaborator
Completed
Health-Related Quality of Life in Gay Men With Localized Prostate Cancer (External Link)
OBJECTIVES: - To enroll 200 gay men with localized prostate cancer in a cross-sectional study of prostate cancer outcomes. - To complete an R01 application using pilot data collected from …
Baylor Role:
Lead Sponsor
Completed
Evaluating Symptom Management Educational Materials for Patients With Prostate Cancer (External Link)
OBJECTIVES: - To collect formative evaluation data about a new educational intervention using focus groups of patients with prostate cancer. - To use the focus group data in the master's …
Baylor Role:
Lead Sponsor