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Completed
Metabolomics for Biomarker Discovery in Children With EoE (External Link)
Eosinophilic esophagitis (EoE) is a disorder of the esophagus triggered by food and/or environmental allergens and is characterized by symptoms of esophageal dysfunction and eosinophilia of the esophagus. The standard …
Baylor Role:
Collaborator
Completed
Gravity Assisted Technique for Esophageal Endoscopic Submucosal Dissection (ESD) (External Link)
Early precancerous esophageal lesions and esophageal cancer, are a threatening illnesses with high mortality rate, so the early intervention is critical during the course of treatment, statistically, every year an …
Baylor Role:
Lead Sponsor
Completed
Efficacy of Audio Recorded Guided Imagery vs Deep Breathing Exercises on Functional Gastrointestinal Pain Disorders (External Link)
Children managed in primary care with a functional gastrointestinal pain disorder will be recruited and studied for this trial. After participants are deemed eligible, they will complete multiple questionnaires and …
Baylor Role:
Lead Sponsor
Completed
Detection of Exocrine Pancreatic Insufficiency in Patients With Diarrhea and Bloating (External Link)
Exocrine pancreatic insufficiency (EPI) diagnosis can be challenging due to several reasons. First, the main symptoms of EPI such as diarrhea, loose stool, bloating or weight loss have low specificity …
Baylor Role:
Lead Sponsor
Completed
NextSteps Intervention for Advanced Cancer Patients and Caregivers (External Link)
In this study, 200 advanced cancer patients who are within one month of treatment initiation (baseline) and their caregivers will complete baseline surveys and be randomized to NextSTEPS or a …
Baylor Role:
Lead Sponsor
Completed
The Feasibility of Self or Partner-assisted Digital Anal Exam Screening (External Link)
There is no standard screening protocol for anal cancer even as disease incidence and mortality increases; however, a digital anorectal exam (also called a digital rectal exam) will play a …
Baylor Role:
Collaborator
Completed
Microbiome Fructan Metabolism and Symptoms in Childhood IBS (External Link)
Fructans (fructo-oligosaccharides) are a type of carbohydrate which can not be hydrolyzed by humans. It is commonly found in wheat in the American diet. After ingestion they arrive essentially intact …
Baylor Role:
Lead Sponsor
Completed
Fecal Microbiota Transplantation (FMT) for Treatment of Ulcerative Colitis in Children (External Link)
FMT RECIPIENTS: Participants will be recruited from the patient population treated by the Pediatric Gastroenterology, Hepatology, and Nutrition Section at Baylor College of Medicine/Texas Children's Hospital. I. Activities prior to …
Baylor Role:
Lead Sponsor
Completed
Non-invasive Biomarkers of Fibrosis in Pediatric Liver Diseases (External Link)
Abnormal liver biochemical and function tests are frequently detected in symptomatic patients since many screening blood test panels routinely include them. A population-based survey in the United States conducted between …
Baylor Role:
Lead Sponsor
Completed
Pancreas Resection With and Without Drains (External Link)
The rate of pancreatic fistula after pancreas resection is about 10% and surgeons have traditionally placed drains near the pancreatic anastomosis to control this potentially very serious complication. In recent …
Baylor Role:
Lead Sponsor