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Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Congenital Abnormalities
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Completed
'TOTAL' (Tracheal Occlusion To Accelerate Lung Growth) Trial (External Link)
This is a multi-center, non-blinded randomized controlled trial in fetuses with isolated moderate CDH, i.e. moderate lung hypoplasia (as determined by prenatal assessment of lung development). It essentially compares fetal …
Baylor Role:
Collaborator
Completed
Fetal Endotracheal Occlusion (FETO) in Severe and Extremely Severe Congenital Diaphragmatic Hernia (External Link)
Enrollment Women carrying fetuses with severe or extremely severe CDH and a normal karyotype will undergo routine clinical evaluation. The fetuses will be 27+0/7 to 29+6/7 weeks of gestational age …
Baylor Role:
Collaborator
Completed
Fetal Surgery for Moderate Left Sided Congenital Diaphragmatic Hernia. (External Link)
Isolated Congenital Diaphragmatic Hernia (CDH) can be diagnosed in the prenatal period, and remains associated with a 30 % chance of perinatal death and morbidity mainly because of pulmonary hypoplasia …
Baylor Role:
Collaborator