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Search Clinical Trials
Completed
Glutathione and Function in HIV Patients (External Link)
Detailed data are not as yet available
Baylor Role:
Lead Sponsor
Completed
Safety and Immunogenicity of Co-Administered Hookworm Vaccine Candidates Na-GST-1 and Na-APR-1 in Gabonese Adults (External Link)
Double-blind, randomized, controlled dose-escalation Phase 1 clinical trial in hookworm exposed adults. Study site: Centre de Recherches Médicales de Lambaréné Number of participants: 32 in 2 cohorts of 16 Doses …
Baylor Role:
Lead Sponsor
Completed
Biomarker Guided Therapies in Stage A/B Heart Failure (External Link)
Recently the investigators have shown that HF risk prediction can be improved using cardiac troponin T measured with a novel high-sensitivity assay (hs-cTnT) and N-terminal pro-B-type natriuretic peptide (NT-proBNP). Furthermore, …
Baylor Role:
Collaborator
Completed
Safety and Immunogenicity Study of Na-GST-1 With or Without CpG (External Link)
This is a Phase 1 randomized double-blind dose-escalation clinical trial in healthy hookworm-naïve adults conducted at the George Washington Medical Faculty Associates, Washington, DC, and the George Washington University School …
Baylor Role:
Lead Sponsor
Completed
Comparative Efficacy of Phenylbutyrate (PBA) vs. Benzoate in Urea Cycle Disorders (External Link)
The investigators will study and compare how effectively sodium phenylbutyrate, sodium benzoate, and a combination of the two, help excrete nitrogen in healthy volunteers. Subject participation will require three, separate, …
Baylor Role:
Lead Sponsor
Completed
Nitric Oxide Supplementation in Argininosuccinic Aciduria (External Link)
The investigators will perform a double blind, randomized, placebo-controlled, crossover study of NO supplementation in ASA patients assessing endothelial function and blood pressure as primary endpoints, and markers of nitric …
Baylor Role:
Lead Sponsor
Completed
Peanut Oral Immunotherapy in Children With Peanut Allergy (Peanut Flour) (External Link)
This is a phase I, open label study for the initial 12 month desensitization phase of peanut oral immunotherapy and a 2 year maintenance phase. Subjects will be recruited to …
Baylor Role:
Lead Sponsor
Completed
A Trial Comparing Single Intra-op Dose of Methadone Versus Placebo in Patients Undergoing Spine Surgery (External Link)
Scoliosis is a disease that involves lateral and/or rotational deformity of the spine and can affect up to 4% of the population. Typically, surgery is considered when Cobb's angle, which …
Baylor Role:
Lead Sponsor
Completed
Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse (External Link)
The noradrenergic system, especially the alpha 1-adrenergic receptor, may play an important role in cocaine addiction in humans. Doxazosin is a long-acting and selective alpha 1-adrenergic receptor blocker, which inhibits …
Baylor Role:
Collaborator
Completed
Individualized High Dose Methotrexate to Treat Cancer in Children Who Have a Significant Risk for Side Effects to Methotrexate (External Link)
The study participant will receive the drug methotrexate as a patient in the hospital. High dose methotrexate will be given as a 24-hour infusion as part of the care determined …
Baylor Role:
Lead Sponsor