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Completed
Pain After Laparoscopic Cholecystectomy With Bilateral Tranversus Abdominis Plane (TAP) Block Versus Local Anesthetic Infiltration (External Link)
The purpose if to find out if analgesia with bilateral ultrasound-guided Tranversus Abdominis Plane (TAP) block with Ropivacaine 0.5% is better than analgesia with local infiltration of trochar sites with …
Baylor Role:
Lead Sponsor
Completed
The Management of Glucocorticoid-Induced Hyperglycemia in Hospitalized Patients (External Link)
The target fasting serum glucose (FSG) and pre-meal SG was 90-140 mg/dL, and the random SG was less than 180 mg/dL, taking into consideration the ADA/AACE target glucose levels in …
Baylor Role:
Lead Sponsor
Completed
Multisite Controlled Trial of Cocaine Vaccine (External Link)
This 18-week, placebo-controlled randomized clinical trial among 300 cocaine dependent patients is designed to test the efficacy of a newly developed active vaccine against cocaine (TA-CD). TA-CD vaccine consists of …
Baylor Role:
Lead Sponsor
Completed
Pain After Laparoscopic Cholecystectomy (External Link)
To the investigators' knowledge, no study has looked at differences in postoperative pain when comparing maintenance of anesthesia with isoflurane, desflurane, sevoflurane, and propofol in laparoscopic cholecystectomy. The investigators' hypothesis …
Baylor Role:
Lead Sponsor
Completed
The Efficacy of Doxazosin for Cocaine Users (External Link)
The NE system, especially the alpha 1-adrenergic receptor, may play an important role in cocaine addiction in humans. The results of this study will provide medical safety data on the …
Baylor Role:
Lead Sponsor
Completed
Nepicastat for Posttraumatic Stress Disorder (PTSD) in OIF/OEF Veterans (External Link)
HYPOTHESES Primary Hypothesis: Compared to placebo treatment, nepicastat-treated OIF/OEF veterans with PTSD will have significantly reduced PTSD hyperarousal symptoms as defined by the Clinician Administered PTSD Scale [CAPS], subscale D …
Baylor Role:
Collaborator
Completed
An ACE Inhibitor (Perindopril) or an Angiotensin Receptor Blocker (Candesartan) as a Treatment for Methamphetamine Dependence (External Link)
Our preliminary data indicate that the ACE inhibitor perindopril can attenuate MA-induced drug craving, suggesting that perindopril should be evaluated as a treatment for MA dependence. Candesartan works similarly to …
Baylor Role:
Lead Sponsor
Completed
Evaluation of Calcium, Vitamin D, Magnesium, and Zinc Absorption in Children (External Link)
We plan to stratify subjects for randomization to either vitamin D supplements or placebo by serum 25-hydroxyvitamin D (25 OHD) into three groups: 0-20 ng/mL, 20-32 ng/mL, and >32 ng/mL. …
Baylor Role:
Lead Sponsor
Completed
BMI and Its Relationship to Hypoglycemic Seizures in Children With Insulin-requiring Diabetes (External Link)
This is a retrospective study using questionnaire/survey/interview. We will give subjects a letter stating the purpose and describing the study. We will answer all questions they have about the study. …
Baylor Role:
Lead Sponsor
Completed
Impact of Vitamin D Status on Bones in Breastfed Infants (External Link)
In recent years, severe vitamin D deficiency has resurfaced as a major public health concern. Nutritional rickets is widespread, and a recent report on this disease in Texas showed Hispanic …
Baylor Role:
Lead Sponsor