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Completed
Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse (External Link)
The noradrenergic system, especially the alpha 1-adrenergic receptor, may play an important role in cocaine addiction in humans. Doxazosin is a long-acting and selective alpha 1-adrenergic receptor blocker, which inhibits …
Baylor Role:
Collaborator
Completed
Bicuspid Valve Aortopathy Feasibility Study (External Link)
The study will consider all patients with a bicuspid aortic valve and 1) determine the number of patients needed to be screened for a clinical trial, based on patient eligibility …
Baylor Role:
Collaborator
Completed
A Safety Study of NNZ-2566 in Patients With Rett Syndrome (External Link)
Rett Syndrome is a developmental disorder primarily if not exclusively affecting females. The disorder is characterized by apparent normal development in early infancy (6-18 months), followed by a period of …
Baylor Role:
Collaborator
Completed
Effects of Dry Eye Treatments on the Ocular Surface (External Link)
This study evaluated the effects of the corticosteroid dexamethasone on suppressing development of eye irritation, cornea epithelial disease and increased production of inflammatory mediators in subjects who were subjected to …
Baylor Role:
Lead Sponsor
Completed
Encapsulated Calcium Absorption in Pregnancy (External Link)
This study will enroll at least 60 pregnant women in a randomized cross-over study in Dhaka, Bangladesh. Each participant will be randomized to one of 3 calcium doses: 500 mg, …
Baylor Role:
Collaborator
Completed
Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Performed Under General Anesthesia Versus Moderate Sedation (External Link)
The purpose of the study is to determine if there are any differences in yield or safety of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) (a type of bronchoscopy with biopsy) …
Baylor Role:
Lead Sponsor
Completed
Tranexamic Acid (TA) vs Combined Oral Contraceptive (COCP) Pilot Study (External Link)
Subjects were randomized to one of two groups (group A or B). Group A received oral tranexamic acid at 1300 mg (two 650mg tablets), three times each day on days …
Baylor Role:
Lead Sponsor
Completed
A Comparison of UGBRS Block and Local Infiltration (External Link)
Laparoscopic appendectomy is a common procedure in pediatric surgery. For single incision laparoscopic appendectomy (SILA), the laparoscope and other instruments are inserted with the aid of a large trocar through …
Baylor Role:
Lead Sponsor
Completed
Study of Dopamine Versus Vasopressin for Treatment of Low Blood Pressure in Low Birth Weight Infants (External Link)
Hypotension in the low birth weight (LBW) and extremely low birth weight (ELBW) infant is often encountered in the postnatal adaptation phase. Severe, prolonged hypotension contributes to cellular dysfunction and …
Baylor Role:
Lead Sponsor
Completed
Radioactive Iodide Therapy for Pediatric Graves' Disease (External Link)
Primary Aims. The investigators propose to assess the safety of 131I use in children with hyperthyroidism due to Graves' disease (GD). The investigators will measure whole body radiation exposure following …
Baylor Role:
Collaborator