Featured

Status

Health Topics

Any Category
Diseases
Neoplasms
Clear Filters

Search Clinical Trials

101 Results
Completed
Psychosocial and Patient Education Needs of Prostate Cancer Patients Selecting Watchful Waiting
Interviews are conducted over the telephone and require approximately 90 minutes to complete. Men interviewed are compensated for their participation in the study.
Baylor Role: Lead Sponsor
Completed
Screening for Bladder Cancer
Reduction of cancer mortality is a stated goal of the National Cancer Institute. Cancer of the bladder is the 4th most commonly diagnosed cancer and 7th leading cause of cancer …
Baylor Role: Lead Sponsor
Completed
Tamoxifen for Progressive Transitional Cell Carcinoma Following Previous Chemotherapy Treatment
The major objective of this two-stage phase II study is to determine whether tamoxifen is deserving of further study in metastatic bladder cancer. Tamoxifen is expected to function as a …
Completed
Phase I - Pre-Radical Prostatectomy RTVP-1 Gene Therapy for Prostate Cancer
The population selected for this study includes patients with locally advanced and/or poorly differentiated tumors. These patients have an unacceptably high failure rate when treated by radical prostatectomy alone (over …
Baylor Role: Lead Sponsor
Withdrawn
Symptom Management in African-American Men With Localized Prostate Cancer
OBJECTIVES: - Develop a symptom management intervention for African-American men treated for localized prostate cancer, with a particular emphasis on low health literacy men. OUTLINE: Participants are interviewed by the …
Baylor Role: Lead Sponsor
Completed
Vaccine Therapy in Treating Patients With Metastatic, Progressive Prostate Cancer
OBJECTIVES: Primary - Evaluate the safety and tolerance of NY-ESO-1/LAGE-1 class-I and class-II vaccine administered subcutaneously in patients with androgen-independent metastatic prostate cancer. Secondary - Compare the response induced by …
Baylor Role: Lead Sponsor
Completed
Phase 1 Intrathecal Topotecan for Neoplastic Meningitis
This is a multi-center, non-randomized pharmacokinetically-guided optimal dosing study of intraventricular topotecan in children with neoplastic meningitis. Topotecan will be administered daily for five consecutive days utilizing the schema shown …
Baylor Role: Lead Sponsor
Completed
Subtotal Resection of Large Acoustic Neuromas With Possible Stereotactic Radiation Therapy
The current standard treatment of a large tumor of the balance nerve (acoustic neuroma or vestibular schwannoma) is surgical resection. Complete removal of such tumor is associated with significant risks …
Baylor Role: Collaborator
Withdrawn
Temozolomide and Topotecan in Treating Patients With Primary CNS Lymphoma
OBJECTIVES: Primary - Determine the complete radiologic response rate in patients with primary CNS lymphoma treated with salvage chemotherapy comprising temozolomide and topotecan. Secondary - Determine the median and failure-free …
Baylor Role: Collaborator
Completed
Taxotere and Adriamycin/Cytoxan (AC) Validation in Breast Cancer Patients
Large clinical trials have confirmed the value of systemic adjuvant therapy in decreasing the risk of recurrence and death in patients with early breast cancer. However, the need to identify …
Baylor Role: Collaborator