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Recruiting
Safe Babies: Parenting Action Plan ( PAP ) (External Link)
The purpose of this project is to evaluate whether prevention education using motivational interviewing focused on promoting positive maternal mental health, coping with inconsolable crying, life stress reduction, and positive …
Baylor Role: Lead Sponsor
Recruiting
Pediatric Dose Optimization for Seizures in Emergency Medical Services (External Link)
The Pediatric Dose Optimization for Seizures in Emergency Medical Services (PediDOSE) study is designed to improve how paramedics treat seizures in children on ambulances. Seizures are one of the most …
Baylor Role: Collaborator
Recruiting
Rett Syndrome Registry (External Link)
The Rett Syndrome Registry is a longitudinal observational study of individuals with MECP2 mutations and a diagnosis of Rett syndrome. Designed together with the IRSF Rett Syndrome Center of Excellence …
Baylor Role: Collaborator
Recruiting
Cardiopulmonary Outcomes in Osteogenesis Imperfecta: BBD7708 (External Link)
This study is cross-sectional. At the participant's one study visit, data will be obtained at a single point in time and reflect the patients' current condition. Evaluations will include family …
Baylor Role: Lead Sponsor
Recruiting
Clear Aligners for the Treatment of Dental Malocclusion in OI (External Link)
Osteogenesis imperfecta (OI) is a heritable connective tissue disorder leading to frequent fractures and bone deformities. In about 90% of individuals with OI, the disease is caused by dominant mutations …
Baylor Role: Lead Sponsor
Recruiting
Imaging-Guided Low Intensity Focused Ultrasound (LIFU) (External Link)
The current project will investigate a novel neurostimulation approach, low intensity focused ultrasound (LIFU), which combines non-invasiveness and a sharp spatial focus in deep brain regions. This open-label early feasibility …
Baylor Role: Lead Sponsor
Recruiting
HER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children With Ependymoma (External Link)
PBTC-059 is a multicenter, Phase I and Surgical study of the treatment HER2-specific CAR T cells for patients with refractory or recurrent ependymoma. Phase I The primary objectives of the …
Baylor Role: Collaborator
Recruiting
Nasotracheal Intubation With VL vs DL in Infants Trial (External Link)
The primary objectives of the study are to compare the nasotracheal intubation (NTI) first attempt success rate using VL vs. DL in infants 0-365 days of age presenting for cardiothoracic …
Baylor Role: Collaborator
Recruiting
Uterine Transplant for Women With Absolute Uterine Factor Infertility (AUFI) (External Link)
BACKGROUND: The feasibility of uterine transplant has been studied for more than a decade. The clinical concept and the technical aspects were first tested and proven in non-primates and then …
Recruiting
Oxytocin for Hypermobile Ehlers-Danlos Syndrome (External Link)
This will be a single-site study to evaluate the effect of IV oxytocin on chronic pain in female adult patients with hypermobile EDS. Oxytocin secretion in the body is dynamic …
Baylor Role: Lead Sponsor