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Active, Not Recruiting
MyChoice: An Application of the Three-Factor Eating Questionnaire (TFEQ-R18v2) Among Adolescent and Young Adult Survivors of Central Nervous System (CNS) Tumors (External Link)
A one-time assessment will be conducted for all participants through the Assessment Center website. No treatment or intervention will be provided. Two websites will be set up (Site A and …
Baylor Role:
Collaborator
Recruiting
Accuracy, Yield and Clinical Impact of a Low-Cost HRME in the Early Diagnosis of Esophageal Adenocarcinoma (External Link)
Primary outcomes: - the diagnostic yield (defined as the proportion of mucosal biopsy samples with neoplasia) of HRME with directed biopsy - compared to standard white-light endoscopy with 4-quadrant random …
Baylor Role:
Collaborator
Completed
Most Closely HLA-Matched CTLs for Relapsed Epstein Barr Virus(EBV)-Associated Diseases (External Link)
First, we will search our cell bank to see if there is a CTL line that is a match with the subject and his/her donor. This matching is done using …
Baylor Role:
Lead Sponsor
Withdrawn
Study of Metformin With Simvastatin for Men With Prostate Carcinoma (External Link)
Men who participate in this study will take both metformin and simvastatin every day. Both drugs are pills and can be taken at home. Subjects will be asked to take …
Completed
Pancreas Resection With and Without Drains (External Link)
The rate of pancreatic fistula after pancreas resection is about 10% and surgeons have traditionally placed drains near the pancreatic anastomosis to control this potentially very serious complication. In recent …
Baylor Role:
Lead Sponsor
Terminated
Everolimus (RAD001) For Advanced Renal Cell Carcinoma (RCC) Before Kidney Removal (External Link)
Everolimus has significantly improved outcomes following prior therapy. This study is a biomarker driven Phase II trial that will assess the activity of everolimus as first-line therapy for renal cell …
Terminated
Administration of CMV-Specific Cytotoxic T Cells in Patients With Glioblastoma Multiforme (External Link)
To generate CMV-T cells we put a specially produced carrier virus (adenovirus) that carries one CMV gene into the patient's blood monocytes or dendritic cells. These cells are then used …
Baylor Role:
Lead Sponsor
Completed
Umbilical Cord Blood Transplant for Children With Myeloid Hematological Malignancies (External Link)
The following will be given as the conditioning regimen for the transplant: BUSULFAN: Busulfan (intravenous BUSULFEX) dosing will be as follows: patients <12 kg: 1.1 mg/kg/dose IV every 6 hours …
Baylor Role:
Lead Sponsor
Completed
Carboplatin and Docetaxel Followed by Epstein-Barr Virus Cytotoxic T Lymphocytes (External Link)
A blood sample will be obtained to start making the CTLs before the patient begins chemotherapy. The patients EBV-specific T cells will be grown while the patient is being treated …
Baylor Role:
Lead Sponsor
Completed
Prostate Cancer Symptom Management for Low Literacy Men (External Link)
Prostate cancer has recently surpassed lung cancer to become the most common cancer of American men. The estimated number of new prostate cancer cases in 2005 is expected to be …
Baylor Role:
Lead Sponsor