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Completed
Pimavanserin Treatment in TS (External Link)
Tourette Syndrome is typically treated with drugs that block or reduce the function of dopamine (a brain chemical involved in movement). However, many of these drugs have adverse effects including …
Completed
VITAL Start: Brief Facility-based Video Intervention (External Link)
Universal HIV testing and treatment can accelerate population-level ART initiation and is critical to realize the UNAIDS 90-90-90 goals. Malawi pioneered Option B+ (B+), a novel application of test-and-treat that …
Baylor Role: Lead Sponsor
Completed
Fit 5 Kids Screen Time Reduction Curriculum for Latino Preschoolers (External Link)
Screen time is a major risk factor for childhood obesity and inadequate physical activity, both of which are determinants of type 2 diabetes (T2D), cardiovascular disease, and multiple cancers. Latinos …
Baylor Role: Collaborator
Completed
Intranasal Dexmedetomidine Sedation in Children for Non-painful Procedures (External Link)
Dexmedetomidine (DEX) is an alpha-2 receptor agonist with sedative, anxiolytic, and analgesics properties. DEX has been used extensively for sedation in children to facilitate different non-painful procedures, such magnetic resonance …
Baylor Role: Collaborator
Completed
Electrophysiological Biomarkers of AV-101 (External Link)
Background: Suicide is the 10th leading cause of death in the US, and is 2-7 times higher in Veterans than age- and sex-matched civilians. Standard psychiatric medications (such as lithium) …
Completed
NMDA Receptor Modulation for Hyperarousal in PTSD (External Link)
This study aims to provide a rigorous test of functional target engagement and "go/no go" milestones for a subsequent POC trial. Investigator will conduct a parallel-arm, randomized, double-blind, placebo-controlled study …
Baylor Role: Lead Sponsor
Completed
Assessment of a PERT-free Nutritional Therapeutic Delivery System for Cystic Fibrosis (External Link)
This is a single center, randomized, double-blind, cross-over trial (with a follow-on single-blind safety evaluation stage), assessing a ready-to-drink nutritional supplement used without PERT ("PERT-free"), nutritional supplement for blood lipid …
Baylor Role: Collaborator
Completed
Feasibility of Healthy Dads Healthy Kids Latino (External Link)
This is a feasibility study of a culturally adapted version of Healthy Dads Healthy Kids for Hispanic families, called Papás Saludables, Niños Saludables. It is a father-targeted program for child …
Baylor Role: Lead Sponsor
Completed
Promoting the Psychological Health of Women With SCI: A Virtual World Intervention (External Link)
The purpose of this project is to test the efficacy of an internet-based psychological health enhancement program for women with spinal cord injury. The intervention will occur in Second Life …
Baylor Role: Collaborator
Completed
Intraoperative Investigation of a Directional Lead and Local Field Potentials for the Optimization of Stimulation Efficacy (External Link)
This is a feasibility study designed to evaluate the usefulness of intraoperative LFP recordings obtained from the implanted DBS lead to predict ideal stimulation parameters. Additionally this study will compare …
Baylor Role: Collaborator