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Active, Not Recruiting
The CSF Shunt Entry Site Trial (External Link)
The study is a multi-centered, randomized, controlled trial comparing two commonly used CSF shunt insertion techniques, anterior and posterior entry site. There is conflicting information and opinions in the pediatric …
Baylor Role: Lead Sponsor
Active, Not Recruiting
TGF-beta Resistant Cytotoxic T-lymphocytes in Treatment of EBV-positive Nasopharyngeal Carcinoma / RESIST-NPC (External Link)
Blood will be collected from the patient to make LMP/BARF1/EBNA1 (NPC)-specific T cells. To grow NPC-specific T cells we have to use special cells called antigen-presenting cells, which train the …
Baylor Role: Lead Sponsor
Active, Not Recruiting
The Houston HIIT-BAC for African Americans (External Link)
The study hypothesis is that the addition of a holistic, home-based environmental exposure reduction and asthma control intervention to enhanced in-clinic care will result in statistically significant improvements in key …
Baylor Role: Lead Sponsor
Active, Not Recruiting
International Fetal Anesthesia Database (External Link)
Advances in technology have allowed for an increase in procedures performed on the fetus in utero; these procedures involve the administration of different anesthetics (sedative- hypnotic agents and or volatile …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Calmer Life: Treating Worry Among Older Adults In Underserved, Low-income, Minority Communities (External Link)
The purpose of this research study is to see how helpful two different interventions offered through the Calmer Life program are in reducing worry and improving mood. The investigators also …
Baylor Role: Lead Sponsor
Active, Not Recruiting
BEnefits of Stroke Treatment Delivered Using a Mobile Stroke Unit (External Link)
There are many ways that use of a MSU might prove valuable in stroke patients, but we will focus on acute ischemic stroke (AIS) and treatment with IV tissue plasminogen …
Baylor Role: Collaborator
Active, Not Recruiting
Fetoscopic Meningomyelocele Repair Study (External Link)
Spina bifida can be a devastating neurological congenital anomaly . It results from incomplete closure of the neural tube between 22 and 28 embryological days. Its incidence is approximately 1-2 …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Microbiome And Multi'Omics In Preterm Birth: The Bacteria And Birth Study (External Link)
Specific Aim 1. Longitudinal maternal (vaginal, oral, skin, gut), fetal (oral, skin, gut) and placental (basal plate and parenchyma) 16S-based metagenomic profiling with inferred metagenomics will reveal distinct microbial communities …
Baylor Role: Lead Sponsor
Active, Not Recruiting
Activated T Lymphocytes Expressing CARs, Relapsed CD19+ Malignancies Post-Allo HSCT(CARPASCIO) (External Link)
The subject or his/her donor will give blood to make CD19/CD28 chimeric receptor-T cells in the laboratory. These cells will be grown and frozen. To make the T cells, the …
Baylor Role: Lead Sponsor
Active, Not Recruiting
iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma and Neuroblastoma (External Link)
Patients give blood to make GD2-T cells that are grown and frozen. To get the GD2-CAR to attach to the surface of the T-cell, a gene is inserted into the …
Baylor Role: Lead Sponsor