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Addition of Lactobacillus to Metronidazole in Treatment of CDAD (External Link)
Clostridium difficile associated disease (CDAD), which nearly always follows antibiotic therapy, has become increasingly common and important in American hospitals, causing substantial morbidity and mortality. Metronidazole is the recommended treatment …
Baylor Role: Collaborator
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Varenicline-Methamphetamine Interaction Study (2008) (External Link)
See Brief Summary
Baylor Role: Lead Sponsor
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Study of LMP1- and LMP2- Specific Cytotoxic T-Lymphocytes (CTL) (External Link)
While patients with nasopharyngeal carcinoma (NPC) may be cured by chemotherapy and radiotherapy, the outlook for patients who are resistant to this treatment or who relapse is poor. Almost all …
Baylor Role: Lead Sponsor
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Rituximab for GVHD (External Link)
Acute graft-versus-host disease (aGVHD), one of the most important complications of allogeneic hematopoietic stem cell transplantation (HSCT) is associated with significant morbidity and mortality. Grades II to IV aGVHD occur …
Baylor Role: Lead Sponsor
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Initiation of Chronic Asthma Care Regimens in the Pediatric Emergency Department (External Link)
This study is a health outcomes intervention trial that utilizes a randomized clinical trial (non-placebo controlled) with two separate arms. The study will be conducted in the ED of Texas …
Baylor Role: Lead Sponsor
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Acamprosate for Treatment of Compulsive Behaviors and Craving in Parkinson's Disease (External Link)
The purpose of this study is to determine how many patients with Parkinson's disease have compulsive behaviors, and what types of behaviors they have. This study will also determine if …
Baylor Role: Lead Sponsor
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Symptom Management in African-American Men With Localized Prostate Cancer (External Link)
OBJECTIVES: - Develop a symptom management intervention for African-American men treated for localized prostate cancer, with a particular emphasis on low health literacy men. OUTLINE: Participants are interviewed by the …
Baylor Role: Lead Sponsor
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Lymphocytic B-Leukemia (B-CLL) w/Human IL-2 Gene Modified & Human CD40 Ligand-Expressing Autologous Tumor Cells (External Link)
This is a phase I trial to assess the safety of depleting regulatory T (Treg) cells using 1-3 doses of an interleukin-2 immunotoxin directed to the CD25 antigen (denileukin diftitox, …
Baylor Role: Lead Sponsor
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Pharmacogenomics in Pulmonary Arterial Hypertension (External Link)
This study will make use of a large population of well defined patients with Pulmonary Arterial Hypertension who were enrolled in Encysive Pharmaceutical's STRIDE clinical trials or who have received …
Baylor Role: Collaborator
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Temozolomide and Topotecan in Treating Patients With Primary CNS Lymphoma (External Link)
OBJECTIVES: Primary - Determine the complete radiologic response rate in patients with primary CNS lymphoma treated with salvage chemotherapy comprising temozolomide and topotecan. Secondary - Determine the median and failure-free …
Baylor Role: Collaborator