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Completed
Study of Na-ASP-2 Human Hookworm Vaccine in Healthy Adults Without Evidence of Hookworm Infection (External Link)
There is an urgent need for new tools to control human hookworm infection and to reduce its burden of disease in developing countries. This is especially true for children and …
Baylor Role: Lead Sponsor
Completed
Zoledronic Acid (ZOMETA) With Cyclophosphamide With Neuroblastoma and Cortical Bone Involvement (External Link)
Zoledronic Acid (Zometa), a new generation, highly potent bisphosphonate used to treat osteoporosis and hypercalcemia of malignancy, is widely used in adult malignancies with potential for bone metastasis such as …
Baylor Role: Lead Sponsor
Completed
Subtotal Resection of Large Acoustic Neuromas With Possible Stereotactic Radiation Therapy (External Link)
The current standard treatment of a large tumor of the balance nerve (acoustic neuroma or vestibular schwannoma) is surgical resection. Complete removal of such tumor is associated with significant risks …
Baylor Role: Collaborator
Completed
The Effect of Diet and Exercise in Heart Failure (External Link)
A growing number of people in this country are overweight or obese. This is concerning as increasing weight has been shown to increase the risk of developing heart failure. However, …
Baylor Role: Lead Sponsor
Completed
Association Between Response to Treatment of C. Diff Colitis and Anti-C.Diff Toxin Antibody (External Link)
Clostridium difficile is the leading cause of nosocomial diarrheal disease associated with antibiotic therapy. This is a debilitating condition with substantial morbidity and mortality that may be around 2-3%. Current …
Baylor Role: Collaborator
Completed
Family Lifestyle Overweight Prevention Program (External Link)
The overall objective of this study is to compare the effectiveness of a behavioral, family-based weight management program and a self-help only group for the prevention of obesity in adolescents. …
Baylor Role: Lead Sponsor
Completed
Pharmacogenetics of Disulfiram for Cocaine (External Link)
Dopamine, a type of neurotransmitter, is the brain's "feel good" chemical. The amount of dopamine in the body may be an important factor in how cocaine addicts respond to treatment. …
Baylor Role: Lead Sponsor
Completed
A Culturally Sensitive Values-Guided Aid for End of Life Decision-Making (External Link)
Background: End-of-life decision-making is an important aspect of providing quality healthcare, especially for the elderly population. Increasingly, the appropriateness of many of these decisions is being questioned. Some invasive procedures …
Baylor Role: Collaborator
Completed
Lantus in the Treatment of Type 1 Diabetes Children (External Link)
The landmark report of the diabetes control and complications trial (DCCT) trial has shown that intensive management delays and/or prevents complications in small vessels associated with Type 1 diabetes (T1DM). …
Baylor Role: Lead Sponsor
Completed
Pedestrian Behavior Following Implementation of a Walking School Bus (External Link)
Walking to school is associated with higher levels of physical activity, which is an objective of Healthy People 2010. However, parents' concerns about safety have been identified as a barrier …
Baylor Role: Collaborator