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Terminated
Efficacy of Micro-Patterned Foley Catheter to Reduce Catheter-Associated Urinary Tract Infection (External Link)
Roughly half of the two million nosocomial infections that occur each year are associated with the use of a medical device. Approximately 30 million urinary catheters are inserted each year …
Baylor Role:
Lead Sponsor
Unknown Status
OnabotulinumtoxinA (onaBoNT-A) Versus Oral Oxybutynin ER (External Link)
Current treatment of neurogenic bladder dysfunction (NGB) is limited by the suboptimal results achieved using standard antimuscarinic agents. A prominent role for the actions of alternative transmitters/growth factors in peripheral …
Terminated
Everolimus (RAD001) For Advanced Renal Cell Carcinoma (RCC) Before Kidney Removal (External Link)
Everolimus has significantly improved outcomes following prior therapy. This study is a biomarker driven Phase II trial that will assess the activity of everolimus as first-line therapy for renal cell …
Completed
Treatment and/or Prevention of Urinary Tract Infections (External Link)
A 7-day treatment with a 28-day follow up has been designed as a "before and after" assessment of the clinical signs and symptoms of an uncomplicated urinary tract infection and …
Baylor Role:
Collaborator
Terminated
Genetic Susceptibility to Kidney Cancer (External Link)
This study will further the understanding of the genetic events leading to the development of RCC; explore the genetic basis for genetic instability and how it affects cancer risk; and …
Baylor Role:
Lead Sponsor
Completed
Health-Related Quality of Life in Patients With Bladder Cancer (External Link)
OBJECTIVES: - To identify aspects of survivorship experience that differ by clinical risk (low risk vs high risk) in patients with non-invasive bladder cancer. - To collect and examine data …
Completed
Quality of Life and Symptom Management in Patients With Bladder Cancer (External Link)
OBJECTIVES: Primary - To identify aspects of health-related quality of life (HRQOL) and symptom management in patients with non-invasive, low- or high-risk bladder cancer. - To obtain feedback on data …
Unknown Status
Bacteriuria Eradication Through Probiotics (External Link)
In children with spina bifida and neurogenic bladder dysfunction, the need for intermittent bladder catheterization increases the risk of bacteriuria. In many patients, this leads to a clinically significant urinary …
Baylor Role:
Lead Sponsor
Completed
Bladder Cancer Patient-Reported Outcomes (External Link)
The purpose of this study is to identify aspects of the bladder cancer (BlCa) survivorship experience that differ by clinical risk at diagnosis. The investigators will collect cross-sectional data from …
Baylor Role:
Lead Sponsor
Terminated
Botox-A Injection to Improve Bladder Function in Early Spinal Cord Injury (#H-20344) (External Link)
Approximately 10,000 spinal cord injuries (SCI) occur each year, most of which occur in males (80%). Many of these patients develop neurogenic bladder dysfunction (NGB) characterized by overactivity of the …
Baylor Role:
Lead Sponsor