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Completed
A Trial Of Oral Chloral Hydrate Versus Intranasal Dexmedetomidine For Sedated Abr Exams (External Link)
The purpose of this study is to compare the efficacy of oral chloral hydrate to intranasal dexmedetomidine for the successful completion of a sedated ABR exam (hearing exam).
Baylor Role:
Lead Sponsor
Completed
A Comparison of UGBRS Block and Local Infiltration (External Link)
Laparoscopic appendectomy is a common procedure in pediatric surgery. For single incision laparoscopic appendectomy (SILA), the laparoscope and other instruments are inserted with the aid of a large trocar through …
Baylor Role:
Lead Sponsor
Terminated
Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF) (External Link)
The STAR-too study is a randomized, open label, multi-center study in CF patients with new MRSA isolated from the respiratory tract (sputum or oropharyngeal (OP) swab). The purpose of the …
Baylor Role:
Collaborator
Terminated
A Comparison of UGSB and GA to IV Narcotics and GA for Post-Op Pain in Children With Supracondylar Fractures. (External Link)
Written consent will be obtained by the investigators prior to the surgical procedure using the Institutional Review Board (IRB) approved consent form. The medical record will be examined and the …
Baylor Role:
Lead Sponsor
Active, Not Recruiting
Randomized Trial of Lenalidomide, Bortezomib, Dexamethasone vs High-Dose Treatment With SCT in MM Patients up to Age 65 (External Link)
The drugs, lenalidomide, bortezomib, and dexamethasone, are approved by the FDA. They have not been approved in the combination for multiple myeloma or any other type of cancer. Bortezomib is …
Baylor Role:
Collaborator
Completed
Modafinil - Escitalopram Study for Cocaine Dependence (External Link)
In this application, we propose an augmentation strategy intended to improve the efficacy of modafinil as a potential treatment for cocaine dependence. Recent data indicates that during chronic treatment modafinil …
Baylor Role:
Lead Sponsor
Terminated
Mission Connect Mild Traumatic Brain Injury (TBI) Integrated Clinical Protocol (External Link)
Of the more than 1.5 million people who experience a traumatic brain injury (TBI) each year in the United States, as many as 75% sustain a mild TBI (MTBI) which …
Baylor Role:
Lead Sponsor
Completed
Investigation of Cycloserine as a Smoking Cessation Treatment (External Link)
See brief summary
Baylor Role:
Lead Sponsor
Withdrawn
Addition of Lactobacillus to Metronidazole in Treatment of CDAD (External Link)
Clostridium difficile associated disease (CDAD), which nearly always follows antibiotic therapy, has become increasingly common and important in American hospitals, causing substantial morbidity and mortality. Metronidazole is the recommended treatment …
Baylor Role:
Collaborator
Completed
Sequential and Hybrid Therapies for H Pylori Infection (External Link)
The purpose of this study is to test whether the 14-day sequential therapy ( esomeprazole plus amoxicillin dual therapy for 7 days followed by triple therapy with esomeprazole, clarithromycin, and …
Baylor Role:
Collaborator