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Completed
Pain and Anxiety Management With Oral Narcotic for Pediatric Suture Repair (External Link)
A prospective, double-blind, placebo-controlled, randomized clinical trial in a tertiary care pediatric emergency department with an annual census of 80,000 visits per year. Patients will be randomized by a randomization …
Baylor Role: Lead Sponsor
Completed
MethaCholine Bronchoprovocation Study (MeCIS) (External Link)
The study consists of two phases. The first phase is a cross-sectional, case-control study measuring the sensitivity and specificity of methacholine challenge testing for differentiating asthmatic participants from non-asthmatic controls. …
Baylor Role: Collaborator
Completed
Recurrent Abdominal Pain in Children (External Link)
Children with recurrent abdominal pain (RAP) who meet the criteria for irritable bowel syndrome (IBS) will be recruited and studied. They will have been diagnosed by a pediatric gastroenterologist and …
Baylor Role: Lead Sponsor
Completed
Rivastigmine and Huperzine A as Treatments for Cocaine Dependence (External Link)
The purpose of this study is to evaluate the interactions between cocaine and oral rivastigmine and between cocaine and oral huperzine A (HupA). The following Specific Aims are proposed: 1. …
Baylor Role: Lead Sponsor
Completed
Treatment and/or Prevention of Urinary Tract Infections (External Link)
A 7-day treatment with a 28-day follow up has been designed as a "before and after" assessment of the clinical signs and symptoms of an uncomplicated urinary tract infection and …
Baylor Role: Collaborator
Completed
Most Closely HLA Matched Allogeneic Virus Specific Cytotoxic T-Lymphocytes (CTL) (External Link)
Patients may be screened for study entry when they have persistent disease despite standard therapy as defined in the inclusion criteria. At that stage a search will be done of …
Baylor Role: Lead Sponsor
Completed
Optimization of IV Ketamine for Treatment Resistant Depression (External Link)
Existing treatments for major depressive disorder (MDD) generally take weeks to months to exert their maximal benefit. There is an urgent need to develop rapid-acting treatments for MDD. Ketamine, a …
Baylor Role: Lead Sponsor
Completed
Impact of an Online Behavioral Weight Loss Program (External Link)
This study tests the impact of an innovative combination of a fortified beverage (a diet cola containing green tea extract, soluble dextrin fiber, and caffeine) and an online support weight …
Baylor Role: Lead Sponsor
Completed
Compassionate Use of an Intravenous Fish Oil Emulsion in the Treatment of Liver Injury in Infants (External Link)
Inpatient Use of Omegaven: Each family will have the severity of their child's condition explained to them and the available data regarding the benefit of the novel preparation explained using …
Baylor Role: Lead Sponsor
Completed
Efficacy and Safety Study of Nutritional Supplements for Treatments of Dry Eye (External Link)
The purpose of this study is to determine the effectiveness of a nutritional supplement in post-menopausal women age 40 or older with moderate to severe dry eyes. This study is …
Baylor Role: Collaborator