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Completed
Effect of Exenatide on Liver and Heart Fat and Inflammation (External Link)
Type 2 diabetics and insulin resistant individuals have an excess of fat in the liver which is not attributable to alcohol or other known causes of liver disease, a condition …
Baylor Role: Lead Sponsor
Completed
NAC as a Potential Treatment for Methamphetamine Dependence (External Link)
N-acetyl-l-cysteine (NAC) treatment is associated with reduced susceptibility to reinstatement of cocaine seeking behavior in rats (Baker et al 2002) and with reduced cue-induced craving in cocaine-dependent human volunteers (LaRowe …
Baylor Role: Lead Sponsor
Completed
Pharmacogenetics of Doxazosin for Cocaine Dependence (External Link)
The NE system, especially the alpha 1-adrenergic receptor, may play an important role in cocaine addiction in humans. The results of this study will provide medical safety data on the …
Baylor Role: Lead Sponsor
Completed
Safe Passages: Ensuring Quality Transitions From NICU (Neonatal Intensive Care Unit) to Ambulatory Care (External Link)
Infants born prematurely or with complex congenital abnormalities are surviving to discharge in growing numbers and often require significant monitoring and coordination of care in the ambulatory setting. These complicated …
Completed
The Impact of Just-in-time Information on Neonatal Intensive Care Unit (NICU) Discharges (External Link)
The purpose of this protocol is to evaluate the impact of providing "Just-in-Time" information, or physician educational material at the time of discharge, to primary care pediatricians caring for Neonatal …
Completed
Does Pioglitazone Increase the Production of 15-EPI-Lipoxin A4? (External Link)
Type-2 diabetes mellitus is a public health concern. According to the World health organization (WHO), diabetes mellitus affects more than 180 million people worldwide. Type 2 diabetes mellitus accounts for …
Baylor Role: Lead Sponsor
Completed
Lifestyle Intervention Trial in Obese Elderly (External Link)
Obesity causes frailty in obese older adults by exacerbating the age-related decline in physical function. However, appropriate management of obesity in older adults is controversial. Weight loss without exercise could …
Baylor Role: Collaborator
Completed
The Effects of Doxazosin on the Cardiovascular and Subjective Effects of Cocaine (External Link)
Primary Objective: The primary objective is to determine the safety of treatment with doxazosin in cocaine-dependent volunteers by examining hemodynamic and subjective effects of administration of ascending doses of cocaine …
Baylor Role: Lead Sponsor
Completed
Active Video Games and Sustainable Physical Activity (External Link)
The study aims to investigate (1) the temporal trajectory from point of accession of active and inactive video game play in the home environment, (2) the effect of active video …
Baylor Role: Lead Sponsor
Completed
Carboplatin and Docetaxel Followed by Epstein-Barr Virus Cytotoxic T Lymphocytes (External Link)
A blood sample will be obtained to start making the CTLs before the patient begins chemotherapy. The patients EBV-specific T cells will be grown while the patient is being treated …
Baylor Role: Lead Sponsor